Skip to content

The effect of Magnesium in migraine prophylaxis

The effect of prophylactic Magnesium in functional outcome of patients with migraine headache

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT2013010411995N1
Enrollment
110
Registered
2013-04-15
Start date
2012-02-20
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Migraine headache. Migraine

Interventions

Intervention 1: Intervention1: The patients treat with Propranolol (tablet 20 mg, manufactured by Rooz Daru Company) and Magnesium oxide (tablet 250 mg, manufactured by Abidi Company). Intervention 2:
Treatment - Drugs
Placebo
Intervention1: The patients treat with Propranolol (tablet 20 mg, manufactured by Rooz Daru Company) and Magnesium oxide (tablet 250 mg, manufactured by Abidi Company).
Intervention 2: The patients treat with Propranolol (tablet 20 mg, manufactured by Rooz Daru company) and placebo (same Magnesium tablet, contain lactose, manufactured by Ahvaz College of pharmacy).

Sponsors

Vice chancellor for research Ahvaz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
15 Years to 50 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Patients with history of moderate or severe migraine headache with or without aura. Exclusion criteria: Patient lesser than 15 and more than 50 years old. Women with menstrual migraine; history of active peptic ulcer and severe abdominal discomfort; history of diabetes mellitus; asthma; severe depression; heart failure; Pregnancy; Lactation and patients who suffered from other headaches except migraine.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Frequency of headache in month. Timepoint: At admission time,after one month and after 3 month. Method of measurement: Questionnaire form.

Secondary

MeasureTime frame
MIDAS score. Timepoint: At the admission, and after 3 month. Method of measurement: Questionnaire form.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSharareh Ghobadi, MD

Ahvaz Jundishapur University of Medical Sciences

ghobadi.sh@ajums.ac.ir+98 61 1374 3012

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026