Comparing the effect of Zinc sulfate and Zinc gluconate on serum level of Zinc and improvement of acute diarrhea in children under 5 years

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2012123111145N3

Enrollment

150

Registered

2013-03-10

Start date

2013-02-19

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Watery Diarrhea. Gastroenteritis and colitis of unspecified origin

Interventions

Intervention 1: Intervention group:Oral administration of Zinc sulfate 1cc / kg of solution 1% daily. Intervention 2: Intervention group 2: Oral administration of Zinc gluconate 1cc / kg of solutio

Treatment - Drugs

Intervention group:Oral administration of Zinc sulfate 1cc / kg of solution 1% daily

Intervention group 2: Oral administration of Zinc gluconate 1cc / kg of solution 1% daily

Control group: Oral administration of like ORS solution 1cc / kg /daily

Eligibility

Sex/Gender

All

Age

1 Years to 5 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Children hospitalized with acute gastroenteritis in Shahid Beheshti hospital; Aged 1 - 5 years. Exclusion criteria: Dysentery confirmed by stool exam; Axillary temperature equal to or more than 38 ° C.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Stop Diarrhea. Timepoint: Daily. Method of measurement: Study of records & asking from mother.;Duration of diarrhea. Timepoint: Daily. Method of measurement: Study of records & asking from mother.;Frequency of Diarrhea. Timepoint: Daily. Method of measurement: Study of records & asking from mother.;Admission period. Timepoint: at discharge. Method of measurement: Days recorded in dossier.;Serum zinc level. Timepoint: on admission - at discharge. Method of measurement: Blood test.	—

Measure

Time frame

Stop Diarrhea. Timepoint: Daily. Method of measurement: Study of records & asking from mother.;Duration of diarrhea. Timepoint: Daily. Method of measurement: Study of records & asking from mother.;Frequency of Diarrhea. Timepoint: Daily. Method of measurement: Study of records & asking from mother.;Admission period. Timepoint: at discharge. Method of measurement: Days recorded in dossier.;Serum zinc level. Timepoint: on admission - at discharge. Method of measurement: Blood test.

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Countries

Iran (Islamic Republic of)

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026