Effect of Vit E, Vit B6, Calcium and Omega-3 on Treatment of Premenstrual Syndrome.

Comparison the Effect of Vit E, Vit B6, Calcium and Omega-3 on Treatment of Premenstrual Syndrome In Student of Islamic Azad University Sari Branch

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2012123010705N1

Enrollment

200

Registered

2013-01-22

Start date

2011-03-20

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Premenstrual syndrom. Premenstrual Tension Syndrome

Interventions

Intervention 1: Vit E : Receiving vit E 100 mg/day For Three Months. Intervention 2: Calcium 1 gram: Receiving 1 gram Calcium During 7 Days End of Cycle for Three Months. Intervention 3: Capsule of

Treatment - Drugs

Vit E : Receiving vit E 100 mg/day For Three Months

Calcium 1 gram: Receiving 1 gram Calcium During 7 Days End of Cycle for Three Months.

Capsule of Fish Oil: Receiving 1 gram Capsule Every Day for Three Months

Vit B6 : Receiving 40 mg/ Day for Three Months

Placebo: Receiving 1 / Day for Three Months

Eligibility

Sex/Gender

Female

Age

18 Years to 30 Years

Inclusion criteria

Inclusion criteria: Inclusion Criteria: Single Girls, Aged Between 18-30 Years Old, Having Regular Menstrual Cycles, Duration of the Cycle Between 21-35 Days, Having Moderate and Sever Form of Premenstrual Syndrome According to the Standard Questionnaire of Rosignol Bonlender. Exclusion Criteria: Breast Feeding, Use of Oral Contraceptive Pills, Having a History of Psychological Diseases Such as Depression, Traumatic Problems During the Past Two Months, Taking Antidepressants and Herbal Drugs 6 Months Ago.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Severity of Premenstrual Syndrom. Timepoint: Before and Three Months After Treatment. Method of measurement: Rosignol Bonlender Questionnair & Checklist.	—

Secondary

Measure	Time frame
Severity of Physical Symptoms of Premenstrual Syndrom. Timepoint: Before Treatment and Three Months After Treatment. Method of measurement: Rosignol Bonlender Questionnaire.;Severity of Psycological Symptoms of Premenstrual Syndrom. Timepoint: Before Treatment and Three Months After Treatment. Method of measurement: Rosignol Bonlender Questionnaire.;Severity of Premenstrual Syndrom. Timepoint: Before Treatment and Three Months After Treatment. Method of measurement: Rosignol Bonlender Questionnaire.	—

Measure

Time frame

Severity of Physical Symptoms of Premenstrual Syndrom. Timepoint: Before Treatment and Three Months After Treatment. Method of measurement: Rosignol Bonlender Questionnaire.;Severity of Psycological Symptoms of Premenstrual Syndrom. Timepoint: Before Treatment and Three Months After Treatment. Method of measurement: Rosignol Bonlender Questionnaire.;Severity of Premenstrual Syndrom. Timepoint: Before Treatment and Three Months After Treatment. Method of measurement: Rosignol Bonlender Questionnaire.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMandana Zafari

Islamic Azad University Sari Branch

mandanazafari@yahoo.com; mandanazafari@iausari.ac.ir+98 15 1229 2263

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026