The effect of hypertonic glucose infusion on dialysis outcomes and quality of life in non-diabetic patients undergoing hemodialysis

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20121229011923N8

Enrollment

106

Registered

2020-01-01

Start date

2020-02-20

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hemodialysis Patients. Cloudy (hemodialysis) (peritoneal) dialysis effluent

Interventions

Intervention 1: Intervention group: These patients will be dialysed 2 times a week and will receive 50 ml of 50% hypertonic glucose 50% intravenously during dialysis 30 minutes before dialysis. Interv

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Hemodialysis for at least 6 months Lack of other chronic illnesses that lead to disability and have a direct impact on dialysis adequacy (such as severe heart disease, respiratory disease, motor movement disorders, malignant diseases, liver failure).

Exclusion criteria

Exclusion criteria: Acute complications during the study period such as heart and lung resuscitation or hospitalization Unwillingness to continue participating in the study

Design outcomes

Primary

Measure	Time frame
Quality of Life. Timepoint: Before the intervention and two weeks after the intervention. Method of measurement: The KDQOL-SF Questionnaire, a self-report questionnaire designed to examine SF-36 patients' life-threatening illness, was used to examine people's lives. This questionnaire evaluates 12 factors of life and health that include: Cognitive Impairment; . Questionnaire scoring is 0-100, with higher scores indicating better quality of life.;Dialysis adequacy. Timepoint: Before and after the intervention and two weeks after the intervention. Method of measurement: To determine dialysis adequacy, a form of dialysis adequacy information including ultrafiltration specifications, patient weight, dialysis duration, filter removal rate, dialysis flow rate is completed. Dialysis adequacy will be calculated by KT / V dialysis adequacy indicators. KT / V (Clearance time / volume) is a unit without a clear representation of the human body during the time period of the year in question. The target KT / V for dialysis three times a week was 1.4 and a minimum acceptable 1.2 was calculated as Daugirdas II dialysis adequacy.	—

Measure

Time frame

Quality of Life. Timepoint: Before the intervention and two weeks after the intervention. Method of measurement: The KDQOL-SF Questionnaire, a self-report questionnaire designed to examine SF-36 patients' life-threatening illness, was used to examine people's lives. This questionnaire evaluates 12 factors of life and health that include: Cognitive Impairment; . Questionnaire scoring is 0-100, with higher scores indicating better quality of life.;Dialysis adequacy. Timepoint: Before and after the intervention and two weeks after the intervention. Method of measurement: To determine dialysis adequacy, a form of dialysis adequacy information including ultrafiltration specifications, patient weight, dialysis duration, filter removal rate, dialysis flow rate is completed. Dialysis adequacy will be calculated by KT / V dialysis adequacy indicators. KT / V (Clearance time / volume) is a unit without a clear representation of the human body during the time period of the year in question. The target KT / V for dialysis three times a week was 1.4 and a minimum acceptable 1.2 was calculated as Daugirdas II dialysis adequacy.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactAkram Hemmatipour

Shoushtar Faculty of Medical Sciences

hematipour.a64@gmail.com+98 61 3622 2221

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026