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Comparison of the efficacy of Clonidine and Tranexamic Acid on the volume of bleeding during rhinoplasty under general anesthesia: clinical trial

Comparison of the efficacy of Clonidine and Tranexamic Acid on the volume of bleeding during rhinoplasty under general anesthesia: clinical trial

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20121229011923N6
Enrollment
135
Registered
2019-02-18
Start date
2019-02-20
Completion date
Unknown
Last updated
2019-02-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Evaluation of bleeding during nasal surgery. Anticoagulants

Interventions

Intervention 1: First intervention group: clonidine 3 micrograms per kilogram will be given orally 90 minutes before the surgery, and the amount of bleeding will be examined during surgery. Interventi

Sponsors

Shoushtar University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Conscious willingness to participate in research Age between 18-60 years Classification of the American Society of Anesthesiology in Class I and II: Class 1: includes patients with normal health who have no systemic problems, such as cardiovascular, respiratory, gastrointestinal, etc. Class 2: Includes a person with mild systemic disease and disease Is under control and has not caused any limitation for the patient)

Exclusion criteria

Exclusion criteria: Drug addiction, benzodiazepines, liver and kidney failure, diabetes, pulmonary and heart disease, coagulation disorders; History of hypersensitivity to clonidine and Tranexamic Acid (increased blood pressure)

Design outcomes

Primary

MeasureTime frame
Evaluation of bleeding during nasal surgery. Timepoint: During and after nose surgery. Method of measurement: The size of the bleeding will be calculated based on the amount of bleeding accumulated in the suction and the blood-stained gases that will be weighed and the surgeon's vision.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAkram Hemmatipour

Shoushtar University of Medical Sciences

hematipour.a64@gmail.com+98 61 3622 2221

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026