The effect of anesthetic in eye surgery

A comparison of effects dexmedetomidine and propofol in Vitreoretinal surgery under retrobulbar block and Monitored Anesthesia Care.

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

IRCT

Registry ID

IRCT2012122811620N3

Enrollment

Registered

2013-06-28

Start date

2013-07-23

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

local anesthesia. Vitreous prolapse

Interventions

Intervention 1: Intervention group or the group D:Dexmedethomedine1 micrograms /kg as a 10 minute intravenous infusion is administered with a pump.Followed by continuous infusion of 0.4 mg per kg of

Treatment - Drugs

Intervention group or the group D:Dexmedethomedine1 micrograms /kg as a 10 minute intravenous infusion is administered with a pump.Followed by continuous infusion of 0.4 mg per kg of body weight per

Control group or the P group: Propofol at a dose of 0.3 mg / kg in 10 minutes followed by continuous infusion mg/kg/h0.3 done.Then 0.1 mg every 5 minutes as (little by little) is added. And is evalua

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria :ASA1-3; age 18 years old and over who have no contraindications to block retro bulbar. Exclusion criteria : age below 18 years old; patients treated with aspirin or anti-coagulant; uncontrolled hypertension; hyperthyroidism; recurrent cough; drug addiction; hearing impairment; neurological or psychiatric disorder; incomplete block; severe heart disease; a history of sleep apnea and drug allergies .

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Spo2. Timepoint: before, during and postoperation. Method of measurement: pulse oxymetry.;Sedation degree. Timepoint: before, during and postoperation. Method of measurement: RSS,BIS.;Pain degree. Timepoint: before, during and postoperation. Method of measurement: VSA.;Surgery satisfact,patient satisfaction. Timepoint: before, during and postoperation. Method of measurement: 7pointlikert.;Recovery profile. Timepoint: before, during and postoperation. Method of measurement: aldrete.s.;Heart rate. Timepoint: before, during and postoperation. Method of measurement: ECG.;MPA. Timepoint: before, during and postoperation. Method of measurement: manometer.	—

Measure

Time frame

Spo2. Timepoint: before, during and postoperation. Method of measurement: pulse oxymetry.;Sedation degree. Timepoint: before, during and postoperation. Method of measurement: RSS,BIS.;Pain degree. Timepoint: before, during and postoperation. Method of measurement: VSA.;Surgery satisfact,patient satisfaction. Timepoint: before, during and postoperation. Method of measurement: 7pointlikert.;Recovery profile. Timepoint: before, during and postoperation. Method of measurement: aldrete.s.;Heart rate. Timepoint: before, during and postoperation. Method of measurement: ECG.;MPA. Timepoint: before, during and postoperation. Method of measurement: manometer.

—

Secondary

Measure	Time frame
Changes in heart rate and blood pressure. Timepoint: before,during and postoperation. Method of measurement: ECG,Manometer.;Pain. Timepoint: before,during and postoperation. Method of measurement: VAS.;Hypoxemia. Timepoint: before,during and postoperation. Method of measurement: pulseoximeter.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohsen Zyaeifard

Tehran University of Medical Sciences

m-ziyaeifard@tums.ac.ir+98 21 8163 3539

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026