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Comparison of the effectiveness , TENS, embedding, acupuncture and drug therapy .

Comparison of the effectiveness of three treatment methods, TENS, embedding, acupuncture and drug therapy on the level of interleukin 6 and knee osteoarthritis pain.

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20121228011912N7
Enrollment
72
Registered
2023-10-21
Start date
2023-09-23
Completion date
Unknown
Last updated
2023-11-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoartritis knee. Gonarthrosis, unspecified

Interventions

Intervention 1: Intervention group: Embedding with cut-gut thread in 6 points in a sterile way.The duration of treatment is 8 weeks. Intervention 2: Intervention group: 4 times a week and each time fo

Sponsors

Mashhad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
45 Years to 75 Years

Inclusion criteria

Inclusion criteria: Treatment with the diagnosis of knee OA based on the criteria of ACR (American College of Rheumatology) Age 50 to 65 years Only one knee is involved Have a VAS pain score of 4 or higher (visual analogue scale) Be literate Consent to participate in the study

Exclusion criteria

Exclusion criteria: Conflict of 2 knees The surgery has been detailed or is in the process of surgery Knee arthroscopy has been performed in the last year In the last six months, have any therapeutic intervention such as intra-articular injection or acupuncture Having any kind of disease that causes malfunction of the immune system, such as: auto-immune, connective tissue diseases, diabetes, cancer, etc. Have a pacemaker

Design outcomes

Primary

MeasureTime frame
Changes in pain. Timepoint: before intervention and weeks 8, 12 and 16. Method of measurement: on the VAS form.;Measurement of inflammatory factors: IL-6. Timepoint: before intervention and weeks 8, 12 and 16. Method of measurement: bleeding.

Secondary

MeasureTime frame
Changes in the amount of physical activity. Timepoint: before intervention and weeks 8, 12 and 16. Method of measurement: based on the WOMAC form.;Change in quality of life. Timepoint: before intervention and weeks 8, 12 and 16. Method of measurement: questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public Contacthamid reza bahrami

Mashhad University of Medical Sciences

bahramihr@gmail.com+98 51 4422 4519

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026