dysmenorrhea and dyspareunia caused by endometriosis. Endometriosis, unspecified
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Diagnosis of clinical endometriosis by observing pain and tenderness in the pelvic examination along with endometriosis nodules in the vaginal examination, firm and motionless uterus and confirmed by ultrasound or MRI (observation of endometriosis cysts and nodules) Diagnosis of grade I-IV endometriosis based on r-ASRM criteria during diagnostic laparoscopy during the previous 12 months Dysmenorrhea complaint with EAPP score >30 or >40 normal pap smear Age 18-45 years Informed written consent to participate in the study
Exclusion criteria
Exclusion criteria: Unwillingness to continue the research Non-adherence to the provided treatment regimen and incorrect or incomplete use of medication Occurrence of any complications attributed to drug use (especially allergies) Endometriosis who were treated with GNRH agonist less than 6 months ago, or danazol or progesterone pills less than 3 months ago, or birth control pills less than one month ago Breastfeeding, pregnancy. Cancers of the uterus, ovaries, cervix and high-grade intraepithelial lesions
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Dysmenorrhea and dyspareunia. Timepoint: At the beginning of the study (before the start of the intervention) and 3 months later. Method of measurement: It will be evaluated using the EAPP checklist scale.;Anti-Müllerian hormone serum level and antral follicle count. Timepoint: At the beginning of the study (before the start of the intervention) and 3 months later. Method of measurement: Measurement of anti-Müllerian hormone serum level and antral follicle count by ultrasound. | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of Life. Timepoint: At the beginning of the study (before the start of the intervention) and 3 months later. Method of measurement: Short form of World Health Organization quality of life questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Mashhad University of Medical Sciences