Comparison of effect and probable complications of two groups of mix of propofol and fentanyl with mix of propofol and ketamin in sedation in patients should be undergoing diagnostic colonoscopy .

Comparison of sedation among Intravenous propofol- fentanyle and propofol- ketamine in patients underwent diagnostic colonoscopy.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2012122711909N1

Enrollment

Registered

2013-03-24

Start date

2013-05-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sedation. Mental and behavioural disorders due to use of sedatives or hypnotics

Interventions

Intervention 1: Intervention 1:propofol0.75 mg/kg with fentanyle 1ug/kg IV. Intervention 2: Intervention2:in a 10cc syringe,1cc ketamin+5cc propofol+4cc water,0.75mg/kg IV.

Treatment - Other

Treatment - Drugs

Intervention 1:propofol0.75 mg/kg with fentanyle 1ug/kg IV

Intervention2:in a 10cc syringe,1cc ketamin+5cc propofol+4cc water,0.75mg/kg IV

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria:age>18years old;age80 years old;cardiovascular disease;coagulopathy;psychatric and neurologic drug user;egg sensitivity.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Sedation. Timepoint: Before and in colonoscopy. Method of measurement: Ramsy score sedation.	—

Secondary

Measure	Time frame
Satisfaction of patiant and physician. Timepoint: End of colonoscopy. Method of measurement: VAS (visual analouge scale).;Recovery. Timepoint: End of colonoscopy. Method of measurement: Time.;Naueia and vomitting. Timepoint: End of colonoscopy. Method of measurement: Observation.;Chilling. Timepoint: End of colonoscopy. Method of measurement: Observation.;Hypoxia. Timepoint: Iin and end of colonoscopy. Method of measurement: Pulse oximetry.;Blood pressure. Timepoint: Before colonoscopy to end of it every 3 minutes. Method of measurement: Monitoring.;Emergency complication of ketamin. Timepoint: End of colonoscopy. Method of measurement: Observation.	—

Measure

Time frame

Satisfaction of patiant and physician. Timepoint: End of colonoscopy. Method of measurement: VAS (visual analouge scale).;Recovery. Timepoint: End of colonoscopy. Method of measurement: Time.;Naueia and vomitting. Timepoint: End of colonoscopy. Method of measurement: Observation.;Chilling. Timepoint: End of colonoscopy. Method of measurement: Observation.;Hypoxia. Timepoint: Iin and end of colonoscopy. Method of measurement: Pulse oximetry.;Blood pressure. Timepoint: Before colonoscopy to end of it every 3 minutes. Method of measurement: Monitoring.;Emergency complication of ketamin. Timepoint: End of colonoscopy. Method of measurement: Observation.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr.Rahimi

Imam Khomeini hospital

Mrahimi@tums.ac.ir+98 21 6119 2828

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026