The effects of oral pregabalin on postoperative pain of lower limb fracture

Evaluation of oral pregabalin effects on postoperative pain control after orthopedic surgery on farcture of lower limbs in Fatemi hospital in 2011

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT201212254093N5

Enrollment

Registered

2013-01-06

Start date

2011-03-21

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

lower limb fracture. Fracture of lower limb, level unspecified

Interventions

Intervention 1: a 150 mg pregabalin capsules 2 hours before surgery. Intervention 2: a placebo capsule 2 hours before surgery.

Prevention

a 150 mg pregabalin capsules 2 hours before surgery

a placebo capsule 2 hours before surgery

Eligibility

Sex/Gender

All

Age

20 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Candidate for lower limb surgery in pelvic, femur and leg under general anesthesia;ASA class I-II Exclusion criteria: Patients with pregnancy;neurological disease;psychiatric disorders; history of seizures; acute or chronic renal disease;history of peptic ulcer;history of allergy to pregabalin or pethidine; taking psychotropic drugs;alcohol or drugs abuse;daily intake of analgesics

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Pain. Timepoint: 2-6-12-24 hours after surgery. Method of measurement: Visual Analogue Scale.	—

Secondary

Measure	Time frame
Sedation. Timepoint: 2-6-12-24 hours after surgery. Method of measurement: ramsay sedation scoring.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Masood Entezariasl

Ardabil University of Medical Sciences

m.entezari@arums.ac.ir+98 45 1772 3010

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026