Effect of alcoholic extract of hibiscus sabdariffa on lipids and inflammatory markers in type 2 diabetic patients

Effect of alcoholic extract of hibiscus sabdariffa on lipid profiles, oxidative stress markers and hs-CRP in type 2 diabetic patients

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT201212251576N2

Enrollment

Registered

2012-12-29

Start date

2012-12-21

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabetes. Non-insulin-dependent diabetes mellitus

Interventions

Intervention 1: Control group recived placebo(corn starch) 3 tablet daily for 3 month. Intervention 2: Intervention group: recived 3 Hyporex-B tablet daiy that contain alcoholic extract of Hibiscuc sa

Placebo

Treatment - Drugs

Control group recived placebo(corn starch) 3 tablet daily for 3 month

Intervention group: recived 3 Hyporex-B tablet daiy that contain alcoholic extract of Hibiscuc sabdariffa for 3 month

Eligibility

Sex/Gender

All

Age

35 Years to 70 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: HbA1c < 8%; LDL < 130 mg/dl; TG< 300 mg/dl; no liver and kidney disease and no concemption of lipid lowering drugs. Exclusion criteria: Hibiscus tea sensivity; unwillingness to continue the study; insulin usage and change the dose of hypoglycemic drugs during the study.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Glucose. Timepoint: Befor intervention and 3 months after intervention. Method of measurement: mg/dl.;HbA1c. Timepoint: Befor intervention and 3 months after intervention. Method of measurement: %.;Total cholesterol. Timepoint: Befor intervention and 3 months after intervention. Method of measurement: mg/dl.;LDL and HDL cholesterol. Timepoint: Befor intervention and 3 months after intervention. Method of measurement: mg/dl.;Triglycerides. Timepoint: Befor intervention and 3 months after intervention. Method of measurement: mg/dl.;Total antioxidants. Timepoint: Befor intervention and 3 months after intervention. Method of measurement: mmol/l.;Hs-CRP. Timepoint: Befor intervention and 3 months after intervention. Method of measurement: ng/ml.	—

Measure

Time frame

Glucose. Timepoint: Befor intervention and 3 months after intervention. Method of measurement: mg/dl.;HbA1c. Timepoint: Befor intervention and 3 months after intervention. Method of measurement: %.;Total cholesterol. Timepoint: Befor intervention and 3 months after intervention. Method of measurement: mg/dl.;LDL and HDL cholesterol. Timepoint: Befor intervention and 3 months after intervention. Method of measurement: mg/dl.;Triglycerides. Timepoint: Befor intervention and 3 months after intervention. Method of measurement: mg/dl.;Total antioxidants. Timepoint: Befor intervention and 3 months after intervention. Method of measurement: mmol/l.;Hs-CRP. Timepoint: Befor intervention and 3 months after intervention. Method of measurement: ng/ml.

—

Secondary

Measure	Time frame
ALT and AST. Timepoint: Befor intervention and 3 months after intervention. Method of measurement: mg/dl.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAli Akbar Rashidi

Kashan University of Medical Sciences

rashidi@kaums.ac.ir+98 36 1555 0021

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026