opium Withdrawal. Mental and behavioural disorders due to psychoactive substance use
Conditions
Interventions
Intervention 1: In methadone group, regarding to a severity of dependence )Based on Addiction Severity Index( mild, moderate, severe, methadone syrup (Made by Exir Company) 15, 30 and 45 mg may be adm
Treatment - Drugs
In methadone group, regarding to a severity of dependence )Based on Addiction Severity Index( mild, moderate, severe, methadone syrup (Made by Exir Company) 15, 30 and 45 mg may be administered, respe
In Tincture of Opium group, regarding to a severity of dependence )Based on Addiction Severity Index( mild, moderate, severe, Tincture of Opium (Made by Daroupakhsh Company) 45, 90 and 135 mg may be a
Sponsors
Vice chancellor for research, Mazandaran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Meeting the DSM-IV-TR criteria for opium dependence; first time detoxification; age range 18- 60 years . Exclusion criteria: Physical illnesses that needed methadone consumption; using other substances (other opioids, cannabinoids, alcohol, benzodiazepines and etc); major psychiatric disorders such as bipolar mood disorder, major depression, severe anxiety disorders and psychotic disorders; major physical diseases such as hepatitis, tuberculosis, AIDS and etc; pregnancy; lactation.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Opium withdrawal sign & symptom. Timepoint: Daily (Within 10 days of drug administration). Method of measurement: Objective Opioid Withdrawal Scale (OOWS). | — |
Secondary
| Measure | Time frame |
|---|---|
| Side effects of drugs. Timepoint: Daily (Within 10 days of drug administration). Method of measurement: Questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSamaneh Farnia MD
Mazandaran University of Medical Sciences
Outcome results
None listed