Snake bite. Snake venom
Conditions
Interventions
Intervention 1: Dexamethasone ampul 0.4mg/kg in 3 devided doses every 8 hours daily till recovery of inflammation. Intervention 2: Sterile water (with an equal volume of 0.4 mg/kg from dexamethasone)i
Treatment - Drugs
Placebo
Dexamethasone ampul 0.4mg/kg in 3 devided doses every 8 hours daily till recovery of inflammation
Sterile water (with an equal volume of 0.4 mg/kg from dexamethasone)in 3 devided doses every 8 hours during admission.
Sponsors
Vice chancellor for research,Ahvaz JondyShapor University of Medical Sciences
Vice chancellor for research,Ahvaz JondyShapor University of Medical Sciences
Eligibility
Sex/Gender
All
Age
15 Years to 65 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria : 1)6 hours from bite, 2)Bite in distal of limbs Exclusion criteria : 1)Recieved antivenum before admission, 2)Underlying disease such as : hypertension, peptic ulcer, heart failure, active infection (e.g. varicella, tuberculosis), psychosis, diabetes, glucoma, osteoprosis and other conditions of corticosteroid's contraindications, 3)Recieved any glucocorticoid or NSAIDS drugs 4)Pregnancy and lactation
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Limb edema. Timepoint: At the admission, 6 hours later, 12 hours later, 18 hours later, second day, third day, other days if admission lenght. Method of measurement: volume of limb according to shift of water in a dish scale in ml. | — |
Secondary
| Measure | Time frame |
|---|---|
| Decrease of limb edema. Timepoint: Each 6 hours within the first day of admission and then daily until disapearance of edema. Method of measurement: Immersion of limb in to the scaled dish of normal saline and determination of volume based on ml. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAhmad Ghorbani,MD
Ahvaz Jundyshapor University of Medical Sciences
Outcome results
None listed