Effects of pravastatin on the prevention of preeclampsia in high-risk pregnant women

Effects of pravastatin on the prevention of preeclampsia in high-risk pregnant women: arandomized controlled clinical trial

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20121224011862N5

Enrollment

Registered

2022-08-30

Start date

2022-09-01

Completion date

Unknown

Last updated

2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pre-eclampsia. Pre-eclampsia

Interventions

Intervention 1: Control group: The group receiving routine prenatal care treatment. Intervention 2: Intervention group: In addition to receiving routine prenatal care, the intervention group will rece

Eligibility

Sex/Gender

Female

Age

18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Pregnant women at high risk for the possibility of preeclampsia Consent to participate in the study Pregnancy age 16 to 20 weeks Having minimum literacy Having a phone number to follow up History of preeclampsia in previous pregnancy In Vitro Fertilization (IVF) Family history of preeclampsia BMI 35 and above Age over 40 years

Exclusion criteria

Exclusion criteria: Uso de anticoagulantes, excepto aspirina. History of allergy to statins Multiple pregnancy History of thrombophilia Chronic kidney disease Autoimmune disease Cardiovascular diseases Smoking and alcohol consumption

Design outcomes

Primary

Measure	Time frame
Preeclampsia. Timepoint: before the intervention (16 weeks of pregnancy), then in the second visit (20 weeks of pregnancy), the third visit (24 weeks of pregnancy), the fourth visit (28 weeks of pregnancy), the fifth visit (30 weeks of pregnancy), sixth visit 32th week of pregnancy), seventh visit (34 th week of pregnancy) and eighth visit (38-40 th week of pregnancy). Method of measurement: mercury sphygmomanometer with a suitable cuff from the right arm in a sitting position after 15 The minute of rest.	—

Measure

Time frame

Preeclampsia. Timepoint: before the intervention (16 weeks of pregnancy), then in the second visit (20 weeks of pregnancy), the third visit (24 weeks of pregnancy), the fourth visit (28 weeks of pregnancy), the fifth visit (30 weeks of pregnancy), sixth visit 32th week of pregnancy), seventh visit (34 th week of pregnancy) and eighth visit (38-40 th week of pregnancy). Method of measurement: mercury sphygmomanometer with a suitable cuff from the right arm in a sitting position after 15 The minute of rest.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr.Farnaz Sahaf

Tabriz University of Medical Sciences

lahroudin@gmail.com+98 35519161

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026