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Effect of high percent oxygen therapy in compared without oxygen therapy on rehabilitation in the first 12 hours of admission in patients with stroke

Effect of high percent oxygen therapy in compared without oxygen therapy on rehabilitation in the first 12 hours of admission in patients with stroke: a randomized clinical trial

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT201212199647N2
Enrollment
52
Registered
2013-11-03
Start date
2012-04-20
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

haemorrhagic or ischemic stroke. Stroke, not specified as haemorrhage or infarction

Interventions

Intervention 1: Intervention group: will receive 50% oxygen in the first 12 hours of admission. Intervention 2: Control group: will receive routine medications without oxygen.
Treatment - Drugs
Intervention group: will receive 50% oxygen in the first 12 hours of admission
Control group: will receive routine medications without oxygen

Sponsors

Vic-chancellor of research and Technology, Hamadan medical university
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 70 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: (a) Age greater than 40 and lesser than 70 years; (b) patients who have GCS greater than 12 and patients that have only brain damage also their airway protective reflexes are normal; (c) The patients that their brain CT scans show pure ischemic and hemorrhagic stroke without need to surgery; (d) The patients that do not have acute subdural hematoma and cerebellar hemorrhage; (e) Elapsed time from accident to starting treatment is less than 12 hours; (f) Patients who are in hemodynamically stable condition and their blood pressure is less than 170/90. Exclusion criteria: (a) patients who have underlying cardiovascular disease, diabetes mellitus, renal failure; (b) Patients who need tracheal intubation at the time of hospital admission; (c) Patients with blood pressure less than 90/60; (d) having documented hypoxia; (e) Patients who had successful CPR; (f) Patients who have history of previous stroke.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Good recovery and less complication. Timepoint: First day of admission, before discharge, six months after discharge. Method of measurement: Ranking scale, Barthel index.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAbbas Taher

Anesthesia and intensive care department

a.taher@umsha.ac.ir; t_anesthesia@yahoo.com+98 81126400634

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026