Migraine Headache. Migraine
Conditions
Interventions
Intervention 1: ?A single dose of 200 mg propofol mixed with 500 ml normal saline within 45 minute. Intervention 2: A single dose 500 mg sodium valproate mixed with 500 ml normal saline within 45 minu
Treatment - Drugs
?A single dose of 200 mg propofol mixed with 500 ml normal saline within 45 minute.
A single dose 500 mg sodium valproate mixed with 500 ml normal saline within 45 minute.
Sponsors
Vice chancellor of Research and Technology, Hamadan University of Medical Science
Eligibility
Sex/Gender
All
Age
20 Years to 50 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Acute migraine attack; 20 to 50 years; ASA=II Exclusion criteria: Patient refuse; Allergy to propofol or sodium valproate; Allergy to egg or soya
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Headache severity. Timepoint: Before administration of drugs and each 15 min during drug infusion and each 30 min for two hours. Also, in patient with reduced severity of pain we will assist pain severity for next 24 and 48 hours. Method of measurement: Numerical Rating Scale (NRS), 0 for without pain and 10 for worst pain. | — |
Secondary
| Measure | Time frame |
|---|---|
| Any side effect such as allergy. Timepoint: Each 15 min during drug infusion and each 30 min for two hours. Also, in patient with reduced pain for next 24 and 48 hours through the telephone. Method of measurement: Ask from patient according to Questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactBehrooz Karkhanei
Hamadan University of Medical Sciences
Outcome results
None listed