Evaluation of intrauterine injection of recombinant human chorionic gonadotropin in improvement of pregnancy rates in in vitro fertilization/intracytoplasmic sperm injection

Evaluation of intrauterine injection of recombinant human chorionic gonadotropin before embryo transfer in improvement of implantation and pregnancy rates in in vitro fertilization/intracytoplasmic sperm injection: a prospective randomised controlled trial study.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2012121711790N1

Enrollment

182

Registered

2012-12-28

Start date

2011-11-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Female Infertility. Female infertility

Interventions

Intervention 1: Intervention group: receiving 250 µg of rhCG as intrauterine injection 12 minutes before ET. Intervention 2: Control group: undergoing ET without a previous intrauterine injection of r

Treatment - Drugs

Intervention group: receiving 250 µg of rhCG as intrauterine injection 12 minutes before ET.

Control group: undergoing ET without a previous intrauterine injection of rhCG.

Eligibility

Sex/Gender

Female

Age

15 Years to 40 Years

Inclusion criteria

Inclusion criteria: The inclusion criteria: female age under 40 years old with infertility. Exclusion criteria: previous IVF/ICSI trials, including a successful trial, endometriosis, azoospermia, uterine myoma or previous myomectomy, or the existence of hydrosalpinges.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Implantation rate. Timepoint: two weeks after embyo transfer. Method of measurement: conventional pregnancy test.;Clinical pregnancy rate. Timepoint: three weeks after a positive pregnancy test. Method of measurement: ultrasound.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMasoumeh Younesi

Shiraz University of Medical Sciences

younesim@sums.ac.ir ; younesi.dr@gmail.com+98 71 1646 2974

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026