Skip to content

Comparison of oral and intravenous ondansetron in the prevention of postoperative nausea and vomiting in cesarean section with spinal anesthesia

Comparison of oral and intravenous ondansetron in the prevention of postoperative nausea and vomiting in cesarean section with spinal anesthesia

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT201212162080N13
Enrollment
162
Registered
2013-06-19
Start date
2012-12-21
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nausea and vomiting. Nausea and vomiting

Interventions

Intervention 1: In group one, patients recived 8 mg(two tablet) ondansetron orallry 30 minutes before surgery and recived 2 ml Distilled water intravenously after spinal anaesthesia. Intervention 2
Prevention
Placebo
In group one, patients recived 8 mg(two tablet) ondansetron orallry 30 minutes before surgery and recived 2 ml Distilled water intravenously after spinal anaesthesia
In group two, patients recived two tablets as same as ondansetron 30 minutes before surgery and recived intravenous 4 mg (2 cc) ondansetron after spinal anaesthesia
In group three, patients recived two tablets as same as ondansetron 30 minutes before surgery and recived 2 ml Distilled water intravenously after spinal anaesthesia

Sponsors

Arak University of Medical Sciences,Vice chancellor for research
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: age between 18-45 and ASA Class I and II Exclusion criteria: history of postoperative nausea and vomiting; history of motion sickness; history of allergy to ondansetron; more than two failure in spinal anaesthesia; history of hyperemesis gravidarum.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Nausea and vomiting. Timepoint: At 0, 1, 2, 4 and 6 hours after arrive to recovery. Method of measurement: Clinical assesment.;Consciousness. Timepoint: At 0, 1, 2, 4 and 6 hours after arrive to recovery. Method of measurement: Using Ramsay score.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Afsaneh Norouzi

Arak University of Medical Sciences

norouzi.a@arakmu.ac.ir; norouzi43@yahoo.com+98 86122247900

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026