Comparison of the effect of bupivacaine injection alone and in association with dexmedetomidine on pain and complications after inguinal hernia surgery

Comparing the effect of injecting Bupivacaine alone and in association with dexmedetomidine through transversus abdominis plane (TAP) block with ultrasound-guided on pain and complications after inguinal hernia surgery: A randomized controlled clinical trial

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20121216011766N5

Enrollment

Registered

2019-04-21

Start date

2019-03-21

Completion date

Unknown

Last updated

2019-05-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Transversus abdominis plane (TAP) block with ultrasound guidance on pain and complications after inguinal hernia surgery. Pelvic and perineal pain

Interventions

Intervention 1: Intervention group:20 milliliters of bupivacaine 0.5% with 1 milliliter (100 micrograms) of dexmedmotidine (Precedex brand containing 200 microgram / 2 milliliter of drug, HOSPIRA manu

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 18 to 65 years old Body mass index 35-18 kilogram / meter 2 Lack of drug sensitivity No alcohol and drug addiction Type of surgery including restoration without tension with mesh ASA class I,II

Exclusion criteria

Exclusion criteria: Surgery lasts more than 2 hours Need for concurrent surgery during inguinal hernia surgery Need to get opium in recovery room excessive hemorrhage Recurrence of hernia Need for spinal anesthesia

Design outcomes

Primary

Measure	Time frame
Comparing the effect of injecting Bupivacaine alone and in association with dexmedetomidine through Transversus Abdominis Plane(TAP) Block with ultrasound guidance in pain and complications after inguinal hernia surgery. Timepoint: In the recovery unit (at 0 o'clock) and at 2, 4, 6, 12, 24 hours after surgery, pain intensity will be measured in the two groups with visual analogue scale (VAS). Method of measurement: In this way, people are asked to show their pain intensity on a 10 cm ruler. no pain will be scored as zero and score 10 is for the highest pain.	—

Measure

Time frame

Comparing the effect of injecting Bupivacaine alone and in association with dexmedetomidine through Transversus Abdominis Plane(TAP) Block with ultrasound guidance in pain and complications after inguinal hernia surgery. Timepoint: In the recovery unit (at 0 o'clock) and at 2, 4, 6, 12, 24 hours after surgery, pain intensity will be measured in the two groups with visual analogue scale (VAS). Method of measurement: In this way, people are asked to show their pain intensity on a 10 cm ruler. no pain will be scored as zero and score 10 is for the highest pain.

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Secondary

Measure	Time frame
In 24 hours after surgery that patients are hospitalized in ward , they will be prescribed 0.5 milligram/kilogram of pethidine, if they need painkillers and they state VAS> 3. Also, complications such as nausea, dizziness and vomiting, the first dose and the mean dose of pethidine consumed in the two groups will be investigated. Timepoint: In the recovery unit (at 0 o'clock) and at 2, 4, 6, 12, 24 hours after surgery. Method of measurement: Nausea, dizziness and vomiting.	—

Measure

Time frame

In 24 hours after surgery that patients are hospitalized in ward , they will be prescribed 0.5 milligram/kilogram of pethidine, if they need painkillers and they state VAS> 3. Also, complications such as nausea, dizziness and vomiting, the first dose and the mean dose of pethidine consumed in the two groups will be investigated. Timepoint: In the recovery unit (at 0 o'clock) and at 2, 4, 6, 12, 24 hours after surgery. Method of measurement: Nausea, dizziness and vomiting.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactHoseein Khoshrang

Rasht University of Medical Sciences

hkhoshrang@yahoo.com+98 132238306

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026