Metabolic syndrome. Metabolic syndrome
Conditions
Interventions
Intervention 1: Intervention group: Daily consumption of two 350 mg capsules that each capsule contains 250 mg of propolis extract and 100 mg of safe and ineffective combination of microcrystalline c
Sponsors
Esfahan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
20 Years to 60 Years
Inclusion criteria
Inclusion criteria: Patients with metabolic syndrome according to (NCEP-ATP III) Willingness to participate in the study Adults 20-60 years old Having the ability to read and write
Exclusion criteria
Exclusion criteria: Pregnancy and lactation Having the following disease: Malignancies or cancer, type I diabetes, nephrotic syndrome, kidney and lung disease, biliary disease, and HIV Sensitivity to bee products Adherence a weight loss diet or physical activity program Tobacco and alcohol consumption Insulin injection Change in the type and dosage of medication from 3 months before entering the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Homeostasis model assessment insulin resistance (HOMA-IR). Timepoint: At the beginning of the study and 12 weeks after supplementation. Method of measurement: ( fasting plasma glucose × fasting Insulin)/22.5. | — |
Secondary
| Measure | Time frame |
|---|---|
| Serum insulin. Timepoint: At the beginning of the study and 12 weeks after supplementation. Method of measurement: Laboratory method.;Fasting blood sugar. Timepoint: At the beginning of the study and 12 weeks after supplementation. Method of measurement: Colorimetric analysis method and by autoanalyzer.;Triglyceride. Timepoint: At the beginning of the study and 12 weeks after supplementation. Method of measurement: Colorimetric analysis method and by autoanalyzer.;Cholesterol. Timepoint: At the beginning of the study and 12 weeks after supplementation. Method of measurement: Colorimetric analysis method and by autoanalyzer.;High-density lipoprotein (HDL). Timepoint: At the beginning of the study and 12 weeks after supplementation. Method of measurement: Colorimetric analysis method and by autoanalyzer.;Low density lipoprotein (LDL). Timepoint: At the beginning of the study and 12 weeks after supplementation. Method of measurement: Colorimetric analysis method and by autoanalyzer.;C-reactive protein (CRP). Timepoint: At the beginning of the study and 12 weeks after supplementation. Method of measurement: Immunoturbidimetric.;Blood pressure. Timepoint: At the beginning of the study and 12 weeks after supplementation. Method of measurement: Barometer.;Weight. Timepoint: At the beginning of the study and 12 weeks after supplementation. Method of measurement: Digital scale.;Waist Circumference. Timepoint: At the beginning of the study and 12 weeks after supplementation. Method of measurement: Non-elastic meter.;Body mass index (BMI). Timepoint: At the beginning of the study and 12 weeks after supplementation. Method of measurement: Weight/ (Height*Height).;Quality of Life. Timepoint: At the beginning of the study and 12 weeks after supplementation. Method of measurement: A validated questionnaire- 36-Item Short Form Health Survey (SF-36).;Mood status (Stress, depression, anxiety). Timepoint: At the beginning of the study and 12 weeks after supplementation. Method of meas | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactGholamreza Askari
Esfahan University of Medical Sciences
Outcome results
None listed