Effect of a-Lipoic acid in patients admitted to intensive care unit (ICU)

Effect of a-Lipoic acid supplementation on total antioxidant capacity , lipids profile and blood presure in patients admitted to intensive care unit (ICU)

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20121216011763N41

Enrollment

Registered

2020-01-10

Start date

2017-06-22

Completion date

Unknown

Last updated

2020-02-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Delirium. Condition 2: meningitis. Condition 3: Diabetes. Delirium due to known physiological condition Bacterial meningitis, unspecified Type 2 diabetes mellitus

Interventions

Intervention 1: Intervention group: Capsule containing 600 mg alpha lipoic acid supplement powder made by Karen Company daily for 2 months. Intervention 2: Control group: Capsule containing 600 mg of

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Patients over the age of 18 are expected to be admitted to the intensive care unit for more than 24 hours. Patients who need special care. cancer patients pregnant women Patients who use other antioxidants

Exclusion criteria

Exclusion criteria: Patient non-cooperation death Not taking more than 20% of supplements and placebo

Design outcomes

Primary

Measure	Time frame
Total antioxidan capacity. Timepoint: Before the intervention and 8 weeks after the intervention. Method of measurement: Spectrophotometric method.	—

Secondary

Measure	Time frame
Lipid profile. Timepoint: Before the intervention and 8 weeks after the intervention. Method of measurement: Biochemical.;Blood pressure. Timepoint: Before the intervention and 8 weeks after the intervention. Method of measurement: Registered on the monitor and cuff mercury barometer.;Malnutrition. Timepoint: Before the intervention and 8 weeks after the intervention. Method of measurement: With Calipers.;Wasit and arm circumfrence. Timepoint: Before the intervention and 8 weeks after the intervention. Method of measurement: Non-elastic tape meters.;Intake of micronutrients and macronutrients. Timepoint: Before the intervention and 8 weeks after the intervention. Method of measurement: 3 dayes record of foods.	—

Measure

Time frame

Lipid profile. Timepoint: Before the intervention and 8 weeks after the intervention. Method of measurement: Biochemical.;Blood pressure. Timepoint: Before the intervention and 8 weeks after the intervention. Method of measurement: Registered on the monitor and cuff mercury barometer.;Malnutrition. Timepoint: Before the intervention and 8 weeks after the intervention. Method of measurement: With Calipers.;Wasit and arm circumfrence. Timepoint: Before the intervention and 8 weeks after the intervention. Method of measurement: Non-elastic tape meters.;Intake of micronutrients and macronutrients. Timepoint: Before the intervention and 8 weeks after the intervention. Method of measurement: 3 dayes record of foods.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr.Nimah Bahreini

Esfahan University of Medical Sciences

Nimahbahreini@yahoo.com+98 31 3792 8032

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026