Dietary approach to stop hypertension (DASH) diet in migraine

The effects of DASH (Dietary approach to stop hypertension) diet on severity, frequency, duration of headache and markers of oxidative stress in migraine patients

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20121216011763N38

Enrollment

100

Registered

2019-10-01

Start date

2019-11-21

Completion date

Unknown

Last updated

2019-11-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Migraine. Migraine without aura

Interventions

Intervention 1: Intervention group: Intervention group will receive DASH diet for 3 months. DASH diet have been designed to be included high levels of fruits, vegetables, whole grains and low fat dair

Eligibility

Sex/Gender

Female

Age

20 Years to 50 Years

Inclusion criteria

Inclusion criteria: Patients who agree to participate in the study Diagnosis of migraine by a neurologist according to ICHD-3 Aged between 20 to 50 years old Body mass index between 18.5-30 kg/m2

Exclusion criteria

Exclusion criteria: Men with migraine Migraine with aura Diagnosis of other disease such as cardiovascular disease, hypertension, diabetes, liver disease, kidney disease, thyroid disorders, malignancies and other neurological problem Pregnancy and lactation

Design outcomes

Primary

Measure	Time frame
Migraine severity. Timepoint: At baseline and after 12 weeks. Method of measurement: Visual analogue scale.;Migraine frequency. Timepoint: At baseline and after 12 weeks. Method of measurement: Clinical examination.;Migraine duration. Timepoint: At baseline and after 12 weeks. Method of measurement: Clinical examination.;Headache impact test. Timepoint: At baseline and after 12 weeks. Method of measurement: HIT questionnaire.;Serum Nitric Oxide. Timepoint: At baseline and after 12 weeks. Method of measurement: Colorimetric method.;Serum vitamin C. Timepoint: At baseline and after 12 weeks. Method of measurement: Colorimetric method.;Total antioxidant capacity. Timepoint: At baseline and after 12 weeks. Method of measurement: Colorimetric method.;Total oxidant capacity. Timepoint: At baseline and after 12 weeks. Method of measurement: Colorimetric method.;Serum glutathion. Timepoint: At baseline and after 12 weeks. Method of measurement: Colorimetric method.	—

Measure

Time frame

Migraine severity. Timepoint: At baseline and after 12 weeks. Method of measurement: Visual analogue scale.;Migraine frequency. Timepoint: At baseline and after 12 weeks. Method of measurement: Clinical examination.;Migraine duration. Timepoint: At baseline and after 12 weeks. Method of measurement: Clinical examination.;Headache impact test. Timepoint: At baseline and after 12 weeks. Method of measurement: HIT questionnaire.;Serum Nitric Oxide. Timepoint: At baseline and after 12 weeks. Method of measurement: Colorimetric method.;Serum vitamin C. Timepoint: At baseline and after 12 weeks. Method of measurement: Colorimetric method.;Total antioxidant capacity. Timepoint: At baseline and after 12 weeks. Method of measurement: Colorimetric method.;Total oxidant capacity. Timepoint: At baseline and after 12 weeks. Method of measurement: Colorimetric method.;Serum glutathion. Timepoint: At baseline and after 12 weeks. Method of measurement: Colorimetric method.

—

Secondary

Measure	Time frame
Blood pressure. Timepoint: At baseline and after 12 weeks. Method of measurement: Sphygmomonometer.;Weight. Timepoint: At baseline and after 12 weeks. Method of measurement: Digital scale.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactGholamreza Askari

Esfahan University of Medical Sciences

askari@mui.ac.ir+98 31 1792 2110

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 14, 2026