Condition 1: Migraine. Condition 2: Migraine. Migraine without aura Migraine with aura
Conditions
Interventions
Intervention 1: The Intervention group will receive three capsules each containing 600 mg of cinnamon powder after each 3 main meals per day for 8 weeks. Cinnamon capsule will be manufactured by Facul
Sponsors
Esfahan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
20 Years to 50 Years
Inclusion criteria
Inclusion criteria: Aged 20-50 years old Diagnose of migraine by a neurologist willing to participate in the study
Exclusion criteria
Exclusion criteria: Pregnancy and breastfeeding Menopause consumption of antioxidants and cinnamon supplements history of cinnamon sensitivity and allergy having tension headaches having chronic diseases such as chronic kidney diseases, gastrointestinal diseases and Alzheimer's
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Severity of migraine attacks. Timepoint: Before the start of the study and 8 weeks after the intervention. Method of measurement: VAS scale.;Frequency of migraine attacks. Timepoint: Before the start of the study and 8 weeks after the intervention. Method of measurement: Questionnaire.;Duration of migraine attacks. Timepoint: Before the start of the study and 8 weeks after the intervention. Method of measurement: Questionnaire.;Migraine Disability Assessment Questioner (MIDAS). Timepoint: Before the start of the study and 8 weeks after the intervention. Method of measurement: Questionnaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| Interleukin 6 (IL6). Timepoint: Before the start of the study and 8 weeks after the intervention. Method of measurement: enzyme-linked immunosorbent assay (ELISA).;Calcitonin Gene-Related Peptide (CGRP). Timepoint: Before the start of the study and 8 weeks after the intervention. Method of measurement: enzyme-linked immunosorbent assay (ELISA).;Weight. Timepoint: Before the start of the study and 8 weeks after the intervention. Method of measurement: Mechanical scales.;Waist Circumference. Timepoint: Before the start of the study and 8 weeks after the intervention. Method of measurement: non-stretching tape measure.;Waist / hip ratio - WHR. Timepoint: Before the start of the study and 8 weeks after the intervention. Method of measurement: non-stretching tape measure.;Body Mass Index. Timepoint: Before intervention and 8 weeks after intervention. Method of measurement: Dividing the weight into kilograms by squared height by meter. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAzadeh Zareie
Esfahan University of Medical Sciences
Outcome results
None listed