Diabetic Polyneuropathy. Type 2 diabetes mellitus with diabetic polyneuropathy
Conditions
Interventions
Intervention 1: Intervention group: Folic acid supplement, tablet 1 mg/day, 8- weeks, Maad pharmacy company. Intervention 2: Control group:placebo, 1 mg/day, 8- weeks, School of Pharmacy Isfahan unive
Treatment - Drugs
Intervention group: Folic acid supplement, tablet 1 mg/day, 8- weeks, Maad pharmacy company
Control group:placebo, 1 mg/day, 8- weeks, School of Pharmacy Isfahan university of medical sciences.
Sponsors
Vice chancellor for research, Isfahan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
20 Years to 80 Years
Inclusion criteria
Inclusion criteria: >20 Years Old Diabetic Neuropathy Approved by the Neurologist Desire to Consume Folic Acid during 8 Weeks
Exclusion criteria
Exclusion criteria: Non-Diabetic Neuropathic Patients Pregnant Women Alcohol Users Smoking Multivitamin-minerals Containing Folic Acid, B12 and B6 Consumers during Study Drugs Consumers that may Interfere with the Absorption Folic Acid such as methotrexate, bacterium, antiepileptic and sulfa antibiotics
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Nerve Conduction Velocity. Timepoint: week 0 and week 8. Method of measurement: EMG-NCV.;Serum folic acid. Timepoint: week 0 and week 8. Method of measurement: Laboratory analysis (blood test).;Serum vitamin B12. Timepoint: week 0 and week 8. Method of measurement: Laboratory analysis (blood test).;Serum homocystein. Timepoint: week 0 and week 8. Method of measurement: Laboratory analysis (blood test). | — |
Secondary
| Measure | Time frame |
|---|---|
| CRP. Timepoint: Week 0 and week 8. Method of measurement: Laboratory analysis (blood test).;HbA1C. Timepoint: Week 0 and week 8. Method of measurement: Laboratory analysis (blood test). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactTayebeh Mottaghi
Isfahan University of Medical Sciences
Outcome results
None listed