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Effect of N-Acetyl cysteine on the success rate of H.pylori eradication

Effect of N-Acetyl cysteine on the success rate of H.pylori eradication

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2012121511738N2
Enrollment
230
Registered
2016-05-17
Start date
2016-04-01
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Helicobacter pylori. Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters

Interventions

Intervention 1: the treatment group are pretreated with NAC groups underfor the 600 mg 2 times a day for a week and then standard triple therapy (amoxicillin 1000 mg 2 times a day, clarithromycin 500
Treatment - Drugs
the treatment group are pretreated with NAC groups underfor the 600 mg 2 times a day for a week and then standard triple therapy (amoxicillin 1000 mg 2 times a day, clarithromycin 500 mg two times dai
Control group treated with standard triple therapy (amoxicillin 1000 mg 2 times a day, clarithromycin 500 mg two times daily and omeprazole 20 mg 2 times a day) are placed.

Sponsors

Vice Chancellor for Research of Tabriz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to No maximum

Inclusion criteria

Inclusion criteria: Inclusion criteria: patients older than 20 years old, HP positive patients at the time of an injection molded pylori eradication indicated they have not previously received eradication regimen, the patients who have NAC in past month. Exclusion criteria: history of gastrectomy, gastric cancer includes adenocarcinoma, previous allergic reaction to antibiotics (amoxicillin and clarithromycin), NAC and proton pump inhibitors (omeprazole), pregnant and lactating women, concurrent severe illness, phenyl ketone Avery, taking antibiotics or NAC now or in the past month and is patient's dissatisfaction.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
The success rate of H pylori eradication regimen. Timepoint: One month after treatment. Method of measurement: Test.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr.Korosh Masnadi Shirazi

Tabriz University of Medical Sciences

Masnadik@tbzmed.ac.ir+98 41 3337 3966

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026