ectopic pregnancy. Ectopic pregnancy
Conditions
Interventions
Intervention 1: MTX (two doses). Intervention 2: laparoscopic salpingostomy.
Treatment - Drugs
Treatment - Surgery
MTX (two doses)
laparoscopic salpingostomy
Sponsors
Vice Chancellor for Research, Tehran University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: inclusion criteria: 1- hemodynamic stability 2- ectopic mass size below 4 cm 3- patients' commitment for complete treatment and follow up 4- absence of MTX treatment contraindication Exclusion criteria: 1- breast feeding 2- immune deficiency 3- abnormalities in hematologic system including anemia, locopenia, thrombocytopenia 4- known hypersensivity reaction to MTX 5- acute respiratory disease 6- acute peptic ulcer 7- alcoholism 8- clinical malfunction of liver and kidney 9- evidence of acute intraabdominal bleeding 10- evidence of cardiac function in the embryo 11- clinical sign and symptom of ectopic pregnancy, or B-hCG level below 5000 IU/L (with mild sign and symptoms)
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| B-hCG level. Timepoint: at the end of study. Method of measurement: blood sampling. | — |
Secondary
| Measure | Time frame |
|---|---|
| Fallopian tubes patency. Timepoint: eight weeks after the time that B-hCG test became negative. Method of measurement: histerosalpingography. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Ladan Kashani
Tehran University of Medical Sciences
Outcome results
None listed