The effect of ondansetrone for prevention of shivering

The effect of preoperative intravenous ondansetrone for prevention of postoperative shivering in patients undergoing gynecologic surgeries with remifentanil-propofol anesthesia

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20121209011700N10

Enrollment

100

Registered

2019-10-21

Start date

2019-08-23

Completion date

Unknown

Last updated

2019-11-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative shivering. Hypothermia, not associated with low environmental temperature

Interventions

Intervention 1: Intervention group: 8 mg ondansetron will be injected before anesthesia begins. Intervention 2: Control group:8 mg normal saline will be injected intravenously before the anesthesia

Eligibility

Sex/Gender

Female

Age

25 Years to 70 Years

Inclusion criteria

Inclusion criteria: Patients with American Society of Anesthesiology (ASA) physical status I or II

Exclusion criteria

Exclusion criteria: Patients with ASA class III or higher Patients with cardiopulmonary diseases Preoperative fever Use of any anti pyretic or anti-inflammatory medication Age range under 25 and over 70 years Addicted patients

Design outcomes

Primary

Measure	Time frame
Shivering due to anesthesia. Timepoint: immediate after the intervention, after 5 minute, after 10 minute, after 20 minute, after 30 minute, . Method of measurement: PAS(five point rating scale).	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr .Farnaz Moslemi

Tabriz University of Medical Sciences

moslemifa@gmail.com+98 41 1553 9161

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026