Randomized comparison of intramuscular pethidine and intravenous fentanyl for pain relief during first stage of labor and their side effects.

Comparison between pethidine & fentanyl effects in painless normal vaginal delivery.

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2012120811504N3

Enrollment

Registered

2013-07-16

Start date

2012-12-08

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Analgesia in Normal Vaginal Delivery. cases with minimal or no assistance, with or without episiotomy delivery in a completely normal case

Interventions

Intervention 1: Pethidin 50 mg IM, repeat q 1-2 hr if needed, maximum dose 100 mg. Intervention 2: Phentanil 50-100 microgram in hr / IV repeat q 1-2 hr if needed.

Treatment - Drugs

Pethidin 50 mg IM, repeat q 1-2 hr if needed, maximum dose 100 mg

Phentanil 50-100 microgram in hr / IV repeat q 1-2 hr if needed

Eligibility

Sex/Gender

Female

Age

18 Years to 40 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: one fetus pregnancy; cephalic presentation; multiparty; GA:38-40wks; trend to painless delivery; patient Blood pressure>90 and heart rate > 60; AGE 18-40 yr. Exclusion criteria: allergy to opium; drug abuse; Wt 100 kg; high risk pregnancy: preeclampsia, severe asthma, insulin dependent diabetes, cardiovascular disease, Myasthenia gravis, epilepsy, liver and kidney disease.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Labor pain. Timepoint: q 15min after first drug injection. Method of measurement: vas(pain score).;Drug. Timepoint: q1hour. Method of measurement: mili litr.;Age. Timepoint: 18 -40. Method of measurement: year.	—

Secondary

Measure	Time frame
Nausea & vomiting. Timepoint: q15min. Method of measurement: observer detection.;FHR. Timepoint: q 15 min. Method of measurement: observer detection.;Apgar. Timepoint: q 15 min. Method of measurement: observer detection.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMojdeh Namdar

Semnan University of Medical Sciences

mojdeh.namdari @yahoo.com+98 21 2258 1441

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026