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Effect of octreotide on urine output during orthotopic Liver transplantation

Effect of octreotide on urine output during orthotopic Liver transplantation

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
IRCT
Registry ID
IRCT2012120411662N1
Enrollment
2012
Registered
2013-07-07
Start date
2011-09-01
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Liver Cirhosis. Fibrosis and cirhosis of liver

Interventions

Intervention 1: In the control group, after induction of anesthesia normal saline will be started with dosage 50 ml in 50 ml syringes intravenously (IV) in 15 minutes and then 50 ml per hour in 50 ml
Treatment - Drugs
In the control group, after induction of anesthesia normal saline will be started with dosage 50 ml in 50 ml syringes intravenously (IV) in 15 minutes and then 50 ml per hour in 50 ml syringes with B
In the octreotide group, after induction of anesthesia octreotide will be started with dosage 50 microgram in 50 ml syringes intravenously (IV) in 15 minutes and then 50 microgram per hour in 50 ml sy

Sponsors

Vice-Chancellery of Research and Technology
Lead Sponsor

Eligibility

Sex/Gender
All
Age
15 Years to 60 Years

Inclusion criteria

Inclusion criteria: All patients with end-stage liver disease who undergoing orthotropic deceased donor liver transplantation from sept 2011 to april 2012 . Patients with history of diabetes mellitus; hypertension; ischemic heart disease ; heart block willbe excluded from study.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Urine Out Put. Timepoint: At the end of hepatectomy phase; Atthe end of an-hepatic phase; At the end of neohepatic phase. Method of measurement: With observation of urine volume per Kg (body weight) per hour.

Secondary

MeasureTime frame
Postoperative Creatinine Level. Timepoint: On the 3rd day postoperation. Method of measurement: Jaffe/kinetic.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Ali Sahmeddini

Shiraz University Of Medical Sciences

sahmeddini@sums.ac.ir+98 71 1647 4270

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026