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Comparison the effects of two anesthetic drugs on agitation of children after anesthesia.

Comparison the effects of Dexmedetomidine and remifentanil on emergence of agitation in children with sevoflurane anesthesia

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20121204011662N14
Enrollment
90
Registered
2020-03-28
Start date
2020-04-20
Completion date
Unknown
Last updated
2020-04-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post operative agitation in children. Restlessness and agitation

Interventions

Intervention 1: Intervention group 1: At the end of anesthesia, patients in group A will receive IV dexmedetomidine 0.1 mcg /Kg over five minutes with a 10 ml syringe with the label A. Intervention 2:

Sponsors

Shiraz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
2 Years to 7 Years

Inclusion criteria

Inclusion criteria: All patients who will candidate for strabismus surgery under general anesthesia

Exclusion criteria

Exclusion criteria: Patients with history of congenital heart disease Patients with history of renal disease Patients with history of liver disease Patients who needs rapid sequence induction Patients with history use of sedative drugs Patients with history of mental retardation Patients with history of psychiatric disorder Patients with history of allergy to drugs will be used in this study.

Design outcomes

Primary

MeasureTime frame
Postoperative agitation. Timepoint: At times: 0, 10 min, 20 min , 30 min after arrival in recovery room. Method of measurement: Pediatric anesthesia emergence delirium scale .;Postoperative pain severity. Timepoint: At times: 0, 10 min, 20 min , 30 min after arrival in recovery room. Method of measurement: Children and infants postoperative pain scale.

Secondary

MeasureTime frame
Mean arterial blood pressure (MAP). Timepoint: Preoperative, Intraoperative, Postoperative. Method of measurement: Non invasive blood pressure monitoring by digital blood pressure measuring of monitoring system.;Heart rate per minute. Timepoint: Preoperative, Intraoperative, Postoperative. Method of measurement: Electrocardiogram.;Satisfaction of the recovery room stuff from children condition. Timepoint: At the end of recovery stay. Method of measurement: Patient's files and records.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammadAli Sahmeddini

Shiraz University of Medical Sciences

sahmeddin@sums.ac.ir+98 71 3647 4270

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026