Keratoconus. Keratoconus
Conditions
Interventions
Intervention 1: Interventional group: After local anaesthesia, the central 7 mm corneal epithelium will be manually removed as 3 or 4 vertical strips about 2 mm wide and 1-mm strips of epithelium will
Treatment - Drugs
Interventional group: After local anaesthesia, the central 7 mm corneal epithelium will be manually removed as 3 or 4 vertical strips about 2 mm wide and 1-mm strips of epithelium will be left untouch
Control group: After local anesthesia, the central 7 mm corneal epithelium will be manually removed as 3 or 4 vertical strips about 2 mm wide and 1-mm strips of epithelium will be left untouched in be
Sponsors
Noor Eye Hospital
Eligibility
Sex/Gender
All
Age
15 Years to 35 Years
Inclusion criteria
Inclusion criteria: The inclusion criterion is the clinical diagnosis of progressive keratoconus with paraclinical confirmation. The criteria of progressive keratoconus is an increase of at least 1D in maximum keratometry, astigmatism, or manifest refraction, or loss of 2 best corrected visual acuity (BCVA) lines or more in the past 12 months. Patients aged 15-35 years old with keratometry less than 55D and a central corneal thickness less than 400 µ will be selected for the study. Patients with other ocular diseases or a history of ocular surgery will be excluded from the study. Participants discontinue the use of the hard and soft contact lens 3 weeks and 3 days prior to the surgery, respectively.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual acuity. Timepoint: pre operative and 1, 3, 6, and 12 months after the procedure. Method of measurement: Snellen chart.;Refraction. Timepoint: pre operative and 1, 3, 6, and 12 months after the procedure. Method of measurement: retinoscope.;Corneal topography. Timepoint: pre operative and 1, 3, 6, and 12 months after the procedure. Method of measurement: pentacam.;Corneal rigidity. Timepoint: pre operative and 1, 3, 6, and 12 months after the procedure. Method of measurement: ORA.;Endothelial cell count. Timepoint: pre operative and 1, 3, 6, and 12 months after the procedure. Method of measurement: non-contact specular microscope. | — |
Secondary
| Measure | Time frame |
|---|---|
| Corneal Haze. Timepoint: 1, 3, 6, and 12 months after surgery. Method of measurement: Opthalmic examination. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSoheila Asgari
Noor Ophthalmology Research Center
Outcome results
None listed