Oral lichen planus.
Conditions
Interventions
Intervention 1: Control Group: Topical corticosteroid in orabase. Intervention 2: Intervention: Cryotherapy with N2O gass.
Treatment - Drugs
Treatment - Devices
Control Group: Topical corticosteroid in orabase
Intervention: Cryotherapy with N2O gass
Sponsors
?Shiraz University of Medical Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Inclusion criteria: • Clinical diagnosis of oral lichen planus • Existence of two lesions with similar clinical appearance (with the size difference of less than 1 cm) on the right and left buccal mucosa or right and left side of tongue • Not received any treatment for the lesions for at least 2 weeks ago • Signing the consent form. Exclusion criteria: • Using drugs that are proved to develop lichenoid lesions. • Lesions seen in contact with dental amalgam • Coexisting dermal and genital lesions • Hypersensitivity to drugs being used • Pregnant women • Systemic disease such as systemic lupus erythematosus, erythema multiform, secondary syphilis, graft versus host disease or others systemic disease.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Reduction in severity of lesions. Timepoint: 2 weeks after treatment. Method of measurement: cilinical judgement of a capable cilinician.;Lesion size. Timepoint: 2, 4, 6, 8, 10, 12 weeks after treatment. Method of measurement: with a digital culis.;Pain. Timepoint: 2, 4, 6, 8, 10, 12 weeks after treatment. Method of measurement: Visual analogue score. | — |
Secondary
| Measure | Time frame |
|---|---|
| Patient satisfaction of each individual treatment. Timepoint: 3 months after treatment. Method of measurement: by asking the patient to give a percentage of satisfaction for each side. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Maryam Zahed
Shiraz University of Medical Sciences, Dental school
Outcome results
None listed