Patients with IVF Failure. In vitro fertilization
Conditions
Interventions
Intervention 1: Intervention group:Tablet Ca-D BID. Intervention 2: Control Group:Tablet of Ca BID.
Treatment - Drugs
Intervention group:Tablet Ca-D BID
Control Group:Tablet of Ca BID
Sponsors
?Avicenna research center
Eligibility
Sex/Gender
Female
Age
20 Years to 35 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: infertile women 20-35 years old with two or more previous IVF failure, without using vitamin D and Calcium from 3 months before. Exclusion criteria:untreated medical disorders; endometriosis; poor responders; hydrosalpinx in ultrasonography; abnormal semen analysis ( Abnormal form>96%,A+B=32%); use of drugs that affect on immune system; thrombophilia (homozygot PAI-I , homozygot C677T, homozygot A1908C, Heterozygot A1908C-C977T); hormonal disorder (FSH>12,PCO); anatomic disorders; genetic disorders and infective disorders
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pregnancy rate. Timepoint: 14 days after embryo transfer. Method of measurement: ßhCG ,14 days after embryo transfer.;Abortion rate. Timepoint: every 2 months. Method of measurement: ßhCG and ultrasonography. | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of embryo. Timepoint: Embryo transfer. Method of measurement: Morfology.;1,25(OH)2D3. Timepoint: Before ovum pick up. Method of measurement: Blood sampling. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Zafardoost Simin
Infertility and recurrent pregnancy loss center
Outcome results
None listed