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Effect of antibiotic therapy on recovery after tonsillectomy and adenotonsillectomy complications

Effect of antibiotic therapy on recovery after tonsillectomy and adenotonsillectomy complications

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2012120211637N1
Enrollment
138
Registered
2013-02-05
Start date
2012-11-20
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Tonsillectomy. Condition 2: Adenotonsillectomy. tonsillectomy Adenectomy

Interventions

Treatment - Drugs
Diagnosis
Intervention 1: Ampicillin intravenously as a single dose of 75 mg per kg before surgery and one dose every 6 hours to 24 hours one and for one week amoxiciline capsul 50 mg per kg every 8 hours. Int
Ampicillin intravenously as a single dose of 75 mg per kg before surgery and one dose every 6 hours to 24 hours one and for one week amoxiciline capsul 50 mg per kg every 8 hours
The control group did not receive any antibiotics.

Sponsors

Birjand Univercity of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Inclusion criterion: all patients admitted for tonsillectomy and adenotonsillectomy in ear, nose and throat department Valiasr Hospital, Birjand, Iran. Exclusion critria: fever (oral temperature greater than 38.2); acute larengopharngyt or evidence of systemic infection in the past three weeks; adenoidectomy alone any type of bleeding disorder (pt, ptt abnormal) and throat disorders like laryngeal cleft palate with underlying diseases (heart disease, respiratory ...) or contraindication for general anesthesia, history of Perry tonsilar abscess, serous otitis media (SOME), evidence of active infection at the time of entry, immunodeficiency, and long-term use of corticosteroids.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Postoperative Recovery and complications. Timepoint: from 4 hours after surgery to one week later. Method of measurement: Nausea and vomiting - oral temperature - bleeding - Time to start drinking fluids - pain -analgesia needed after tonsillectomy and adenotonsillectomy r.

Secondary

MeasureTime frame
Oral tempreture. Timepoint: 4 hours after operation-10 hours after operation-1 week after operation. Method of measurement: mercury thermometer.;Pain. Timepoint: 4 hours after surgery-7 hours after surgery-10 hours after surgery-1 week after surgery. Method of measurement: pain scale Criterion.;Nausea-vommiting. Timepoint: 6 hours after surgery. Method of measurement: Rhodes index.;Bleeding. Timepoint: intra operation-24 hours after operation-24 hours later. Method of measurement: a case history.;White blood cell count. Timepoint: 24 hours after operation. Method of measurement: CBC.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Mohammadreza Mofateh

Birjand University of Medical Sciences

rezamood@bums.ac.ir; yaldajannesar@gmail.com+98 56 1444 0388

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026