Condition 1: abdominal bloating. Condition 2: abdominal bloating. Disease of intestine, unspecified Other specified diseases of digestive system
Conditions
Interventions
Intervention 1: group B: 2 weeks placebo. Intervention 2: group A: two weeks treatment with omeprazole 20 mg twice daily, metronidazole 500 mg twice daily, amoxicillin 1000 mg twice daily, and bismuth
Treatment - Drugs
group B: 2 weeks placebo
group A: two weeks treatment with omeprazole 20 mg twice daily, metronidazole 500 mg twice daily, amoxicillin 1000 mg twice daily, and bismuth subcitrate 240 mg twice a day
Sponsors
Ketmanshah University of Medical Science
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Inclusion criteria: having abdominal bloating symptom during at list 3 months with at least 2 points severity; a positive H.pylory ELISA serologic test. Only patients with score 2 or greater would be included in trial. Exclusion criteria: History of gastrointestinal bleeding; any evidence of malignancy; If any evidence of epigastric pain or burning sensation bye eating; If there is bloating or diarrhea which was triggered with dairy product or gluten containing foods;malabsorption evidences; Bloody diarrhea or fresh rectal bleeding without symptoms only suggestive of hemorrhoid or fissure; Abdominal pain referred to the back or sever positional pain; Previous history of gastrointestinal surgery or resection; Failure to complete treatment period of at least 80%; patient's unwillingness to continue treatment
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Abdominal bloating improvement. Timepoint: just before starting treatment, 2 weeks, 4 and 6 weeks after it. Method of measurement: 5 point likert score. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactBita Anvari
Kermanshah University ofMedical Science
Outcome results
None listed