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effect of normal saline on diarrhea

the comparison between isotonic versus hypotonic rehydration therapy on the level of plasma sodium in children with gastroenteritis

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201211261545N2
Enrollment
112
Registered
2012-12-23
Start date
2012-12-20
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

gasteroenteritis. Noninfective gastroenteritis and colitis, unspecified

Interventions

Intervention 1: First,20cc/kg isotonic saline (0.9%)were administered which could be repeated for 3 times, then 5% dextrose in hypotonic saline(0.45%) with 20meq/Lit were administered as loading and m
Treatment - Other
Treatment - Drugs
First,20cc/kg isotonic saline (0.9%)were administered which could be repeated for 3 times, then 5% dextrose in hypotonic saline(0.45%) with 20meq/Lit were administered as loading and maintenance fluid
First,20cc/kg isotonic saline (0.9%)were administered which could be repeated for 3 times, then 5% dextrose in isonatremic saline(0.9%) with 20meq/Lit were administered as loading and maintenance flui

Sponsors

Vice-chancellor for research -Guilan University of Medical Science
Lead Sponsor

Eligibility

Sex/Gender
All
Age
1 Years to 14 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: age 6 months to 14 years; without Diabetes Insipidus; hypothalamic diseases; pituitary diseases; renal disease; acute pulmonary disease; malnutrition ; cardiac diseases; hyponatremia at T0; hyperatremia at T0 Exclusion criteria: hypernatremia(sodium above 150); Hyponatremia ( Sodium Lower than 130); toxicity; low blood pressure.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Hyponatremia in isonatremic group. Timepoint: 4 hours and 24 hours after reception. Method of measurement: the level ofserum sodium concentrationwere evaluated by ise method in electrolyte analyser.;Hyponatremia in hyponatremic group. Timepoint: 4 hours and 24 hours after reception. Method of measurement: the level ofserum sodium concentrationwere evaluated by ise method in electrolyte analyser.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHamidreza Badeli

Guilan University of Medical Sciences

badeli@gums.ac.ir+98 13 1322 9902

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026