Male Infertility. Complication associated with artificial fertilization, unspecified
Conditions
Interventions
Intervention 1: In intervention group (n=150 oocyte ) after oocytes retrieval, they will be entered to culture media plus 5 mic/ml calcium ionophore for 5 minutes, and then will be washed at least 5
Treatment - Drugs
In intervention group (n=150 oocyte ) after oocytes retrieval, they will be entered to culture media plus 5 mic/ml calcium ionophore for 5 minutes, and then will be washed at least 5 time by mops so
In control(n=150 oocyte ) group usual Intracytoplasmic sperm injection will be performed.
Sponsors
Vise Chancellor of Shahid Sadoughi University of Medical Sciences, Yazd
Eligibility
Sex/Gender
All
Age
18 Years to 39 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Teratospermic men with normal morphology less than 14%,who are candidate for Intracytoplasmic sperm injection Exclusion criteria:women older than 40 years;women with FSH higher than 12; immature oocytes
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fertilization rate. Timepoint: 16-18 houres. Method of measurement: Observation with microscope.;Clinical pregnancy. Timepoint: 2-3 weeks after positive B-hCG. Method of measurement: Observation of fetal heart activity by transvaginal ultrasonography.;Chemical pregnancy. Timepoint: After 14 days of embryo transfer. Method of measurement: Measurement of serum B-hCG. | — |
Secondary
| Measure | Time frame |
|---|---|
| Cell division. Timepoint: Two days. Method of measurement: Observation with microscope.;Emberyo quality. Timepoint: Two days. Method of measurement: Observation by microscope according to the symmetrics and exact of Blastomer pieces. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Sima Janati
Research and Clinical Center for Infertility, Shahid Sadoughi University of Medical Sciences, Yazd
Outcome results
None listed