Obsessive- Cumpulsive Disorder. Obsessive-compulsive disorder
Conditions
Interventions
Intervention 1: Tablet fluvoxamine (100 mg/day) combined with 100 mg/day of Tablets riluzole as intervention group for 8 weeks. Intervention 2: Tablet fluvoxamine (100 mg/day) combined with placebo as
Treatment - Drugs
Placebo
Tablet fluvoxamine (100 mg/day) combined with 100 mg/day of Tablets riluzole as intervention group for 8 weeks
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Inclusion Criteria: 1-Age between 18-60, 2-Diagnosis of OCD based on DSM IV 3 , Minimum Score of 21 on YALE-BROWN Obsessive-Compulsive Scale- Exclusion Criteria:1- Substance dependence,2- IQ less than 70,3-any other mental disorder on axis I, 4-Any serious cardiac, renal or hepatic disease ,5- receiving psychotropic medications during the last 6 weeks 6- pregnancy or breast feeding 7-rising liver transaminases to three times the upper limit of normal or highe
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Severity of symptoms of OCD. Timepoint: Baseline and weeks 2-4-6-8 after beginig of treatment. Method of measurement: Y_BOCS( Yale-Brown obsessive compulsive scale). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactProf. Shahin Akhondzadeh
Tehran University of Medical Sciences
Outcome results
None listed