Efficacy of low-dose hCG adjunct to r-hFSH plus GnRH antagonist for ovarian stimulation in assisted reproductive technology

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT201211197165N2

Enrollment

120

Registered

2012-11-25

Start date

2012-11-21

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

infertility. Female infertility associated with anovulation

Interventions

Intervention 1: r-hFSH + GnRH antagonist. Intervention 2: r-hFSH + GnRH antagonist + low-dose hCG.

Treatment - Drugs

r-hFSH + GnRH antagonist

r-hFSH + GnRH antagonist + low-dose hCG

Eligibility

Sex/Gender

Female

Age

20 Years to 39 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: infertile female patient; age between 20-39 years old; body mass index(BMI) of 20- 25 kg/m2; a normal uterus and two functional ovaries; day 3 FSH level 2 unsuccessful IVF/ICSI attempts; poor ovarian response in previous IVF/ICSI treatment and any endocrine disorders.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Beta-hCG level. Timepoint: 15 days after oocyte retrieval. Method of measurement: By laboratory kit from blood sample.	—

Secondary

Measure	Time frame
Number of mature oocytes. Timepoint: 35-36 hours after high-dose hCG injection. Method of measurement: Transabdominal ultrasound.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Ladan Kashani

Tehran University of Medical Sciences

Kashani_ladan@tums.ac.ir+98 21 7788 3195

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026