The effect of ginger (zingiber officinale) on H.pylori positive non ulcer dyspepsia

The effects of ginger (zingiber officinale)powder and extract on H.pylori erradicationand improvement of clinical signs in patient with H.pylori positive non ulcer dyspepsia

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT201211182017N9

Enrollment

120

Registered

2012-11-28

Start date

2013-02-03

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

functional Dyspepsia. Dyspepsia

Interventions

Intervention 1: Intervention group 1: Receiving 3 g/ day dried ginger powder as 3 tablet for 1 month. Intervention 2: Intervention group 2: Receiving 250 mg/ day ginger extract as 1 tablet for 1 month

Treatment - Drugs

Placebo

Intervention group 1: Receiving 3 g/ day dried ginger powder as 3 tablet for 1 month

Intervention group 2: Receiving 250 mg/ day ginger extract as 1 tablet for 1 month

Control group: Receiving 250 mg/ day isomalt (as placebo) as 1 tablet for 1 month

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: patients aged 65 to 18 years old with dyspeptic symptoms including postprandial fullness, early satiety or upper abdominal pain or burning during the last 3-6 months continuously or intermittently and the endoscopic examination without ulcers, but with H. pylori positive infection based on histological examination or Rapid Urease Test (RUT). Exclusion criteria: age below 18 and above 65 years; peptic ulcer; extreme anorexia; painful swallowing; antibiotics consumption; pregnancy and lactation; having hepatobiliary disease; IBS; jaundice; enlarged lymph nodes in the body; family history of gastric cancer and esophageal history of gastric surgery; frequent vomiting and receiving chemotherapy or NSAIDS intake during the study.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Erradication of H.pylori. Timepoint: before intervention and one month after the end of intervention. Method of measurement: at first by rapid urease test during upper endoscopy and at the end by H.pylori stool antigen test.	—

Secondary

Measure	Time frame
Dyspepsia clinical symptoms. Timepoint: before and after intervention. Method of measurement: clinical examination and ROME III dyspepsia symptoms questionnaire.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactVahideh Ebrahimzadeh Attary

faculty of Health and Nutrition

ebrahimzadeh.va@gmail.com+90 411 382 67 78

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026