Tuberculosis. Tuberculosis of lung, confirmed by sputum microscopy with or without culture
Conditions
Interventions
Intervention 1: In case group Standard anti-tuberculosis treatment for 6 months plus l- arginine, 2 g daily in first month. Intervention 2: In control group 6-month Anti-TB treatment plus placebo 2gra
Treatment - Drugs
In case group Standard anti-tuberculosis treatment for 6 months plus l- arginine, 2 g daily in first month
In control group 6-month Anti-TB treatment plus placebo 2gram daily in first month
Sponsors
Arak University of Medical Sciences
Eligibility
Sex/Gender
All
Age
15 Years to 99 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: adults over 15 years ;New cases of positive sputum smear Exclusion criteria: pregnant women ; aged under 15 years, ;patients who During the past month received L-arginine ; Sensitivity to L - arginine
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improved paraclinical tests. Timepoint: days of 14 , 28 , 42 , 56. Method of measurement: check of CRP.;Improved paraclinical tests. Timepoint: days of 14 , 28 , 42 , 56. Method of measurement: check of ESR.;Improved paraclinical tests. Timepoint: days of 14 , 28 , 42 , 56. Method of measurement: check of CBC. | — |
Secondary
| Measure | Time frame |
|---|---|
| Improve of life quality. Timepoint: 0 and 56. Method of measurement: standard questionairof GHQ-28.;Accelerating weight gain. Timepoint: 0 AND56. Method of measurement: Weight measurement. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactGhazaleh Akbarifard
Arak University of Medical Sciences
Outcome results
None listed