Acute limb trauma. Superficial injury to shoulder and upper arm, Open wound of shoulder and upper arm, fracture of shoulder and upper arm, Dislocation, sprain and strain of joints and ligaments of shoulder girdle, Superficial injury of forearm, Open wound of forearm, Fractu
Conditions
Interventions
Intervention 1: In group 1 or intervention group patients received drug and placebo in 2 syringes that were filled by study headmaster. Both of the syringes contained 10 milliliter of clear liquid.
Sy
build in Iranian drug industry (Daroupakhsh or Abureihan) that diluted to 1 milligram/milliliter for intravenous injection. Intra venous Morphine sulfate prescribed by dose of 0.1 milliliter/kilogram
Treatment - Drugs
In group 1 or intervention group patients received drug and placebo in 2 syringes that were filled by study headmaster. Both of the syringes contained 10 milliliter of clear liquid.
Syringe number 1
In group 2 or control group patients received drugs in 2 syringes that were filled by study headmaster and both of them contained 10 milliliters of clear liquid.
Syringe number 1 contains 10 millilit
Sponsors
The vice chancellor for research,The medical school of Tehran University of Medical Science
Eligibility
Sex/Gender
All
Age
16 Years to 50 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: all patients who presented to our ED and were complaining pain due to acute limb trauma with severity index of pain at least 5 of 10 in Numerical Pain Score (NRS). Exclusion criteria: special group of patients (pregnant, breast feeding); history of respiratory disease such as asthma; patients who were receiving neuroleptic drugs; patients with chronic pain, opium or alcohol addiction or chronic use of analgesics.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain score which is reported by patient. Timepoint: Five, 10, 15, 30 and 60 minutes after receiving drugs. Method of measurement: Questionnaire by Numerical Pain Scale(NRS). | — |
Secondary
| Measure | Time frame |
|---|---|
| Respiratory rate. Timepoint: Five, 10, 15, 30, 60 minutes after receiving drugs. Method of measurement: Questionnaire.;Patient's Global rating of satisfaction. Timepoint: One hour after receiving drug via nebulizer. Method of measurement: Questionnaire.;The period of time between treatment and the onset of analgesia. Timepoint: Five, 10, 15, 30, 60 minutes after receiving drugs. Method of measurement: Questionnaire.;Total dose of rescue dose of Morphine sulfate. Timepoint: Since 15 minutes after receiving drug via nebulizer. Method of measurement: milligram.;The percentage of arterial Oxygen saturation. Timepoint: Five, 10, 15, 30, 60 minutes after receiving drugs. Method of measurement: Percent.;Systolic and diastolic blood pressure. Timepoint: Five, 10, 15, 30, 60 minutes after receiving drugs. Method of measurement: millimeter of mercury.;Heart rate. Timepoint: Five, 10, 15, 30, 60 minutes after receiving drugs. Method of measurement: Beat per minute.;Level of consciousness. Timepoint: Five, 10, 15, 30, 60 minutes after receiving drugs. Method of measurement: Questionnaire.;The number of reported nausea or vomiting. Timepoint: Five, 10, 15, 30, 60 minutes after receiving drugs. Method of measurement: Questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Shervin Farahmand
Tehran University of Medical Science
Outcome results
None listed