Comparing low dose of gabapentin and diclofenac on posthysterectomy pain

The comparison between low dose of gabapentin and diclofenac on postoperative pain in patients undergoing abdominal hysterectomy with general anesthesia

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT2012111710089N2

Enrollment

100

Registered

2013-05-12

Start date

2013-02-19

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postprocedural disorders of genitourinary system, not elsewhere classified. Postprocedural disorder of genitourinary system, unspecified

Interventions

Intervention 1: Prescription of 100 mg rectal suppository diclofenac (Behvazan Pharmaceutical Company) plus oral placebo capsule (?Sobhan Pharmaceutical Company) to control group three times every eig

Treatment - Drugs

Prescription of 100 mg rectal suppository diclofenac (Behvazan Pharmaceutical Company) plus oral placebo capsule (?Sobhan Pharmaceutical Company) to control group three times every eight hours .

Prescription of 300 mg oral gabapentin (Sobhan Pharmaceutical Company) plus rectal suppository placebo (Behvazan Pharmaceutical Company) intervention group three times every eight hours .

Eligibility

Sex/Gender

Female

Age

35 Years to 55 Years

Inclusion criteria

Inclusion criteria: The inclusion criteria: women's age between 35-55 years, informed consent – The exclusion criteria: past history of heart, lung, kidney, GI tract, liver and psychiatric disease, raised of intra-cranial pressure, hypertension, chronic pain disorder, previous surgery, prolonged surgery (upon 2 hours), emergent hysterectomy, infection and ileus after surgery.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Post-operative pain. Timepoint: 2, 4, 6, 12, 24 hours after surgery. Method of measurement: By using VAS SCORE.	—

Secondary

Measure	Time frame
Frequency of nausea. Timepoint: 2,4,6,12,24 hours after surgery. Method of measurement: Question from patient.;Frequency of vomiting. Timepoint: 2,4, 6,12, 24 hours after surgery. Method of measurement: Question from patient.;Frequency of dizziness. Timepoint: 2, 4, 6,12, 24 hours after surgery. Method of measurement: Question from patient.;Frequency of time additive pethedin needed. Timepoint: 2, 4, 6,12, 24 hours after surgery. Method of measurement: Patient’s documents.	—

Measure

Time frame

Frequency of nausea. Timepoint: 2,4,6,12,24 hours after surgery. Method of measurement: Question from patient.;Frequency of vomiting. Timepoint: 2,4, 6,12, 24 hours after surgery. Method of measurement: Question from patient.;Frequency of dizziness. Timepoint: 2, 4, 6,12, 24 hours after surgery. Method of measurement: Question from patient.;Frequency of time additive pethedin needed. Timepoint: 2, 4, 6,12, 24 hours after surgery. Method of measurement: Patient’s documents.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactFaeze Fashkhami

Giulan University of Medical Sciences

h_fertility@gums.ac.ir+98 911 334 1365

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026