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Comparison of amoxicillin and sodium chloride 0.9% in the treatment of sinusitis

Comparison of amoxicillin and sodium chloride 0.9% in the treatment of acute sinusitis in 4-15 years old children

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2012111511470N1
Enrollment
80
Registered
2013-01-31
Start date
2013-03-21
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Sinusitis. Acute sinusitis

Interventions

Intervention 1: Control group use washing the nose with saline 0.9% three times daily and 0.25% phenylephrine 80 mg/kg/day for two days. Intervention 2: Experiment group use washing the nose with sali
Treatment - Drugs
Control group use washing the nose with saline 0.9% three times daily and 0.25% phenylephrine 80 mg/kg/day for two days.
Experiment group use washing the nose with saline 0.9% three times daily and 0.25% phenylephrine 80 mg/kg/day for two days with amoxicillin three times daily for 10-14 days.

Sponsors

Vice Chancellor for Research, Shahrekord Univrsity of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
4 Years to 15 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: nasal congestion, or postnasal drip for more than 10 to 14 days and less than 30 days; fever of 39 degrees or more with purulent nasal discharge for at least 3-4 days. Exclusion criteria: Sensitivity to the antibiotic amoxicillin; antibiotic use in the last month; chronic sinusitis; sinus complications (such Periorbital or orbital edema); a known case of cystic Fibrusis; Gastroesophagus Reflux; abnormal palate, an immune disorder such as IgA deficiency; recurrent sinusitis; immunodeficiency.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Sinusitis symptoms. Timepoint: at base line, two weeks later. Method of measurement: examination.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Abolfazl Khoshdel

Shahrekord University Of Medical Sciences

fazelkh@skums.ac.ir+98 38 1222 0016

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026