female infertility. Female infertility associated with anovulation
Conditions
Interventions
Intervention 1: in Interventional Group 1: with daily usage of 50 mg Clomiphen citrate oral tablet from 3rd to 7th day of menstrual cycle. Intervention 2: In intervention Group 2: Subcutaneously D
Treatment - Drugs
in Interventional Group 1: with daily usage of 50 mg Clomiphen citrate oral tablet from 3rd to 7th day of menstrual cycle.
In intervention Group 2: Subcutaneously Daily injection of 75IU Recombinant Gonadotropine from 4th day of menstrual cycle.
Sponsors
Vice Chanceler for Research Tehran university of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: age lower than 40 years ; the first cycle of treatment;primary infertility; duration of infertility 7.2;viscosity20000000/ml; total sperm count>40000000;motility>50%;forward progresion>2 ; normal morphology>50% ;round cell<5000000/ml;sperm aglutination<2) mild male factor . Exclusion criteria: moderate to severe endometriosis diagnosed with laparascopy;history of prior abdominal or gynecological surgery;history of PID; history of allergy or contraindication for hormonal drug usage .
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical pregnancy. Timepoint: 6-7 weeks after IUI(intra uterine insemination). Method of measurement: sonography and geststional sac detection.;Chemical pregnancy. Timepoint: 2-3 weeks after IUI. Method of measurement: labratory test.;Ongoing pregnancy rate. Timepoint: 20 weeks after IUI. Method of measurement: SONOGRAPHY. | — |
Secondary
| Measure | Time frame |
|---|---|
| Abortion. Timepoint: 20th week of pregnancy. Method of measurement: follow up the patient and do sonography.;Multi gestation pregnancy. Timepoint: 6-7weeks after IUI. Method of measurement: sonography and detection several gestational sacs.;Live birth rate. Timepoint: 36-40th week of pregnancy. Method of measurement: follow up the patient. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactBahareh Khandzad
Tehran University of Medical Sciences
Outcome results
None listed