Hemodialysis. N18.5
Conditions
Interventions
Intervention 1: The 53 hemodialysis patients that are having inclusion criteria are screened with questionnaire. They are randomly divided in two groups( drug and placebo)
Treatment in the drug group
Treatment - Drugs
Placebo
The 53 hemodialysis patients that are having inclusion criteria are screened with questionnaire. They are randomly divided in two groups( drug and placebo)
Treatment in the drug group is started wit
treatment in the placebo group is started with dose of 50mg placebo (one tablet) daily at night and added every 5-7 days 25 mg until reaches to maximum 200mg (with patient tolerance). Then it given wi
Treatment in the drug group is started with dose of 50mg of fluvoxamine (one tablet) daily at night and added every five to seven days 25mg, until reaches to maximum dose 200mg (with patient tolerance
Sponsors
Arak University of Medical Science
Eligibility
Sex/Gender
All
Age
20 Years to 70 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria;hemodialysis patients; filling the testimonial questionnaire;age 20-70 years;thrice weekly hemodialysis;KT/V>0.9(keeping the optimum adequecy of dialysis) exclusion criteria:dermatitis disease;B and C hepatitis;cholestasis and other liver disease;treatment with corticosteroid in recent months;anemia(Hb<10);treatment with other SSRI;TCA;MAOI;5-HT3 receptor antagonist ;phenothiazine;lithium;history of seizure;pregnancy and breastfeeding;hypomania;consumption of theophylinand warfarin;sever chronic nausea;hyponatremia
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pruritus score. Timepoint: before intervention;8 weeks after intervention;20 weeks after intervention. Method of measurement: 5-D questionnaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| Fluvoxamine. Timepoint: weekly. Method of measurement: milligram.;Placebo. Timepoint: weekly. Method of measurement: milligram.;Side effects. Timepoint: weekly. Method of measurement: quallitative. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr.zohreh sadat nikjoo
Arak University of Medical Science
Outcome results
None listed