Melatonin in catamenial migraine headache compare with naproxen

evaluation of melatonin efficacy on frequency and intensity of catamenial migraine headache comparing to naproxen

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20121110011424N4

Enrollment

Registered

2019-05-08

Start date

2018-08-28

Completion date

Unknown

Last updated

2019-05-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Women with Catamenial migraine headache.

Interventions

Intervention 1: Intervention group: women with catamenial migraine treated with Naproxen. Intervention 2: Intervention group: women with catamenial migraine treated with Melatonin.

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: women in fertility age with pure catamenial migraine women in fertility age with migraine headache associated with catamenial headache

Exclusion criteria

Exclusion criteria: patient with other primary headache patient with chronic migraine patient with DM- HTN- peptic ulcer

Design outcomes

Primary

Measure	Time frame
Change in frequency and severity of headache. Timepoint: baseline,1 month after intervention,3 months after intervention. Method of measurement: migraine diary questionnaire.;Sleep change. Timepoint: baseline,1 month after intervention,3 months after intervention. Method of measurement: Berlin sleep questionnaire.	—

Countries

Iran (Islamic Republic of)

Contacts

Public Contactabbas tafakhori

Tehran University of Medical Sciences

abbas.tafakhori@gmail.com+98 21 6119 2424

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 17, 2026