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The effect of Spirulina supplementation on plasma markers of exercise-induced muscle damage

The effect of Spirulina supplementation on plasma markers of exercise-induced muscle damage, IL-6 and antioxidant capacity in Tekwando athletes: a cross-over trail.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20121110011421N4
Enrollment
18
Registered
2021-07-12
Start date
2019-04-09
Completion date
Unknown
Last updated
2021-08-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Exercise-induced muscle damage.

Interventions

This study has two groups. Group 1 receives spirulina in the first period of study and placebo in the second period of study. Group 2 receive placebo in the first period and spirulina in the second pe

Sponsors

Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to 35 Years

Inclusion criteria

Inclusion criteria: Male Taekwondo Athletes Taekwondo athletes with experience of at least 3 years Age from 18 to 35 years

Exclusion criteria

Exclusion criteria: Tobacco and drug use in the last year Use of anti-inflammatory drugs in the last three months Follow special and unusual diets in the last three months Consumers of sports supplements in the last three months Having chronic diseases that require a person to take medicine People weighing less than 40 kg Blood donors during the month before the test People with illness or surgery in the last 3 months

Design outcomes

Primary

MeasureTime frame
Plasma levels of the lactate dehydrogenase enzyme (muscle damage Index). Timepoint: Day 1 after exercise and day 22 after exercise, after a 14-day washout period, again day 1 after exercise and day 22 after exercise (4 time in total). Method of measurement: Elaisa test.;Plasma levels of the creatine kinase enzyme (muscle damage Index). Timepoint: Day 1 after exercise and day 22 after exercise, after a 14-day washout period, again day 1 after exercise and day 22 after exercise (4 time in total). Method of measurement: Elaisa test.;Plasma levels of Interleukin 6. Timepoint: Day 1 after exercise and day 22 after exercise, after a 14-day washout period, again day 1 after exercise and day 22 after exercise (4 time in total). Method of measurement: IL 6 kit.;Total antioxidant capacity (TAC). Timepoint: Day 1 after exercise and day 22 after exercise, after a 14-day washout period, again day 1 after exercise and day 22 after exercise (4 time in total). Method of measurement: Total antioxidant assay kit.;Activity of Super oxide dismutase enzyme (SOD). Timepoint: Day 1 after exercise and day 22 after exercise, after a 14-day washout period, again day 1 after exercise and day 22 after exercise (4 time in total). Method of measurement: Super oxide dismutase assay kit.;Glutathione peroxidase enzyme activity. Timepoint: Day 1 after exercise and day 22 after exercise, after a 14-day washout period, again day 1 after exercise and day 22 after exercise (4 time in total). Method of measurement: Glutathione peroxidase assay kit.;Plasma level of malondialdehyde. Timepoint: Day 1 after exercise and day 22 after exercise, after a 14-day washout period, again day 1 after exercise and day 22 after exercise (4 time in total). Method of measurement: Malondialdeyde assay kit.

Secondary

MeasureTime frame
Weight. Timepoint: Day 1 after exercise and day 22 after exercise, after a 14-day washout period, again day 1 after exercise and day 22 after exercise (4 time in total). Method of measurement: Seca Scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactArvin kashani

Tehran University of Medical Sciences

kashani.arvin@gmail.com+98 21 4436 6496

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 12, 2026