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Therapeutic effect of Montelukast in patients with oral lichen planus

Evaluation of therapeutic effect of Montelukast and Prednison in patients with oral lichen planus

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2012110811389N2
Enrollment
200
Registered
2012-12-24
Start date
2013-01-04
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lichen Planus. Lichen Planus

Interventions

Intervention 1: Montelukast , 10 milligrams oral tablet , first month : daily, one tablet and second month : alternate day, one tablet. Intervention 2: Placebo ,10 milligrams oral tablet , similar
Treatment - Drugs
Placebo
Montelukast , 10 milligrams oral tablet , first month : daily, one tablet and second month : alternate day, one tablet
Placebo ,10 milligrams oral tablet , similar motelukast , first month : daily , one tablet and second month : alternate day , one tablet

Sponsors

Vice Chancellor for Research , Hamedan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 55 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria : (1) Diagnosis of OLP will be carried out by clinical history , physical exams and histopathological findings. (2) All of the patients should not use medication for at least two months. (3) They should not have systemic diseases such as diabetes mellitus, hepatitis and trauma history. Exclusion criteria : Patient is non-compliant with treatment until end of study.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Size of lesion. Timepoint: Study onset/after 2,4,6,8,10,12 weeks. Method of measurement: Ruler or flexible surgical probe.;Pain rate. Timepoint: Study onset/after 2,4,6,8,10,12 weeks. Method of measurement: Visual Analogue Scaling.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHossein Hasannia

Hamedan Dentistry Faculty

dr_hossein78@yahoo.com+98 81 1839 0936

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026