Comparison of two volume and pressure control ventilation modes during laparoscopic bariatric surgeries.

The comparison of two volume and pressure control ventilation modes on the gas exchange and mechanical parameters of respiratory system during laparoscopic bariatric surgeries, a cross over clinical trial.

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20121107011398N14

Enrollment

Registered

2020-05-04

Start date

2019-03-20

Completion date

Unknown

Last updated

2022-01-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obesity. Overweight and obesity

Interventions

Intervention 1: The study protocol being a crossover, each participating patient will receive both types of interventions. The main intervention in the study is the pressure controlled mode of mechani

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Obese patients candidated for bariatric surgeries with body mass index (BMI) 40-55 Patients older than 18 and lower than 60 years ASA physical class < or = class III

Exclusion criteria

Exclusion criteria: Patient dissatisfaction History of sever respiratory disease History of advanced cardiovascular disease

Design outcomes

Primary

Measure	Time frame
O2 saturation (SPo2). Timepoint: Every 5 min during surgery. Method of measurement: With Pulse Oximeter.;End-tidal Co2. Timepoint: Every 5 min during surgery. Method of measurement: With Capnograph.;Peak airway pressure. Timepoint: Every 5 min during surgery. Method of measurement: By the monitor of anesthesia machine.;Arterial blood gas analysis. Timepoint: In 15 and 30 minutes after insufflation of gas into abdominal cavity. Method of measurement: By sending arterial blood sample to laboratory.	—

Measure

Time frame

O2 saturation (SPo2). Timepoint: Every 5 min during surgery. Method of measurement: With Pulse Oximeter.;End-tidal Co2. Timepoint: Every 5 min during surgery. Method of measurement: With Capnograph.;Peak airway pressure. Timepoint: Every 5 min during surgery. Method of measurement: By the monitor of anesthesia machine.;Arterial blood gas analysis. Timepoint: In 15 and 30 minutes after insufflation of gas into abdominal cavity. Method of measurement: By sending arterial blood sample to laboratory.

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Secondary

Measure	Time frame
Exhaled tidal volume. Timepoint: During Surgery. Method of measurement: By anesthesia machine.;Dynamic pulmonary compliance. Timepoint: Every 5 min during surgery. Method of measurement: Calculation of variable by using the amounts of airway pressure and tidal volume.;Respiratory dead space. Timepoint: Every 5 min during surgery. Method of measurement: Calculation by the use of arterial and end tidal PCo2 pressure.	—

Measure

Time frame

Exhaled tidal volume. Timepoint: During Surgery. Method of measurement: By anesthesia machine.;Dynamic pulmonary compliance. Timepoint: Every 5 min during surgery. Method of measurement: Calculation of variable by using the amounts of airway pressure and tidal volume.;Respiratory dead space. Timepoint: Every 5 min during surgery. Method of measurement: Calculation by the use of arterial and end tidal PCo2 pressure.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Reza Ghodraty

Iran University of Medical Sciences

ghodrati.mr@iums.ac.ir+98 21 8894 6762

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026